词条 | Trichodiene synthase |
释义 |
| Name = trichodiene synthase | EC_number = 4.2.3.6 | CAS_number = 101915-76-8 | IUBMB_EC_number = 4/2/3/6 | GO_code = 0045482 | image = | width = | caption = }} In enzymology, a trichodiene synthase ({{EC number|4.2.3.6}}) is an enzyme that catalyzes the chemical reaction trans,trans-farnesyl diphosphate trichodiene + diphosphate Hence, this enzyme has one substrate, trans,trans-farnesyl diphosphate, and two products, trichodiene and diphosphate. This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, trichodiene-forming). Other names in common use include trichodiene synthetase, sesquiterpene cyclase, and trans,trans-farnesyl-diphosphate sesquiterpenoid-lyase. This enzyme participates in terpenoid biosynthesis. Structural studiesAs of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes {{PDB link|1YJ4}}, {{PDB link|1YYQ}}, {{PDB link|1YYR}}, {{PDB link|1YYS}}, {{PDB link|1YYT}}, {{PDB link|1YYU}}, {{PDB link|2AEK}}, {{PDB link|2AEL}}, and {{PDB link|2AET}}. References
2 : EC 4.2.3|Enzymes of known structure |
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