1. Structural studies

2. References

In enzymology, a tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase ({{EC number|2.1.1.61}}) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + tRNA S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate

Thus, the two substrates of this enzyme are S-adenosyl methionine and tRNA, whereas its two products are S-adenosylhomocysteine and tRNA containing 5-methylaminomethyl-2-thiouridylic acid.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:tRNA (5-methylaminomethyl-2-thio-uridylate)-methyltransferase. Other names in common use include transfer ribonucleate 5-methylaminomethyl-2-thiouridylate, 5-methyltransferase, and tRNA 5-methylaminomethyl-2-thiouridylate 5'-methyltransferase.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes {{PDB link|2DER}}, {{PDB link|2DET}}, {{PDB link|2DEU}}, and {{PDB link|2HMA}}.

References

• {{cite journal |vauthors=Taya Y, Nishimura S | date = 1973 | title = Biosynthesis of 5-methylaminomethyl-2-thiouridylate. I. Isolation of a new tRNA-methylase specific for 5-methylaminomethyl-2-thiouridylate | journal = Biochem. Biophys. Res. Commun. | volume = 51 | pages = 1062–8 | pmid = 4703553 | doi = 10.1016/0006-291X(73)90035-1 | issue = 4 }}
• {{cite journal |vauthors=Taya Y, Nishimura S |editor = Salvatore, F. |editor2 = Borek, E. |editor3 = Zappia, V. |editor4 = Williams-Ashman, H.G. |editor5 = Schlenk, F. |title=The Biochemistry of Adenosylmethionine |publisher=Columbia University Press |location=New York | date=1977 |page=251 }}

• The Sensualist by Ruskin Bond
• The Sensualist (Ruskin Bond)
• The Sensual Man
• The Sensual Sound of Sonny Stitt
• The Sensuous Sicilian
• The Sentencing Project
• The Sentimental Bloke (1932 film)
• The Sentimental Bloke (1963 film)
• The Sentimental Bloke (musical)
• The Sentimental Bloke, The Poems of C.J. Dennis
• The Sentimental Lady
• The Sentimental Policeman
• The Sen Times
• The Sentinals
• The Sentinel (Gauhati)
• The Sentinel (Pallas album)
• The Sentinel-Standard
• The Sentinel Standard
• The Sentinel (Stoke-on-Trent)
• The Sentry (novel)
• The Sentry (painting)
• The Seoul Institute
• The Separation
• The Separation (2002 novel)
• These Past 5 Years