“Tryptophan alpha,beta-oxidase”的意思、由来-开放百科全书

词条

Tryptophan alpha,beta-oxidase

释义

References

{{enzyme
| Name = tryptophan alpha,beta-oxidase
| EC_number = 1.3.3.10
| CAS_number = 156859-19-7
| IUBMB_EC_number = 1/3/3/10
| GO_code = 0050621
| image =
| width =
| caption =
}}

In enzymology, a tryptophan alpha,beta-oxidase ({{EC number|1.3.3.10}}) is an enzyme that catalyzes the chemical reaction

L-tryptophan + O₂ alpha,beta-didehydrotryptophan + H₂O₂

Thus, the two substrates of this enzyme are L-tryptophan and O₂, whereas its two products are alpha,beta-didehydrotryptophan and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with oxygen as acceptor. The systematic name of this enzyme class is L-tryptophan:oxygen alpha,beta-oxidoreductase. Other names in common use include L-tryptophan 2',3'-oxidase, and L-tryptophan alpha,beta-dehydrogenase. It employs one cofactor, heme.

References

{{cite journal | vauthors = Genet R, Denoyelle C, Menez A | year = 1994 | title = Purification and partial characterization of an amino acid alpha,beta- dehydrogenase, L-tryptophan 2',3'-oxidase from Chromobacterium violaceum | journal = J. Biol. Chem. | volume = 269 | pages = 18177–84 | pmid = 8027079 | issue = 27 }}
{{cite journal | vauthors = Genet R, Benetti PH, Hammadi A, Menez A | year = 1995 | title = L-tryptophan 2',3'-oxidase from Chromobacterium violaceum. Substrate specificity and mechanistic implications | journal = J. Biol. Chem. | volume = 270 | pages = 23540–5 | pmid = 7559518 | issue = 40 | doi=10.1074/jbc.270.40.23540}}

3 : EC 1.3.3|Heme enzymes|Enzymes of unknown structure

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