“Tryptophan dehydrogenase”的意思、由来-开放百科全书

词条

Tryptophan dehydrogenase

释义

References

{{enzyme
| Name = tryptophan dehydrogenase
| EC_number = 1.4.1.19
| CAS_number = 94047-13-9
| IUBMB_EC_number = 1/4/1/19
| GO_code = 0050363
| image =
| width =
| caption =
}}

In enzymology, a tryptophan dehydrogenase ({{EC number|1.4.1.19}}) is an enzyme that catalyzes the chemical reaction

L-tryptophan + NAD(P)+ + H₂O (indol-3-yl)pyruvate + NH₃ + NAD(P)H + H⁺

The 4 substrates of this enzyme are L-tryptophan, NAD⁺, NADP⁺, and H₂O, whereas its 5 products are (indol-3-yl)pyruvate, NH₃, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-tryptophan:NAD(P)+ oxidoreductase (deaminating). Other names in common use include NAD(P)+-L-tryptophan dehydrogenase, L-tryptophan dehydrogenase, L-Trp-dehydrogenase, and TDH. This enzyme has at least one effector, calcium.

References

{{cite journal | vauthors = Vackova K, Mehta A, Kutacek M | date = 1985 | title = Tryptophan aminotransferase and tryptophan dehydrogenase - activities in some cell compartments of spinach leaves - the effect of calcium-ions on tryptophan dehydrogenase | journal = Biol. Plant. | volume = 27 | pages = 154–158 | doi = 10.1007/BF02902153 | issue = 2–3 }}

4 : EC 1.4.1|NADPH-dependent enzymes|NADH-dependent enzymes|Enzymes of unknown structure

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。