| 词条 | Tuberous sclerosis complex tumor suppressors |
| 释义 |
Resistance to ischemia-reperfusion injury by protein restriction is mediated by activation of the tuberous sclerosis complex.[3] References1. ^1 {{cite journal |vauthors=Dibble CC, Elis W, Menon S, Qin W, Klekota J, Asara JM, Finan PM, Kwiatkowski DJ, Murphy LO, Manning BD | title=TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1 | journal= Molecular Cell | volume=47 | issue=4 | year=2012 | pages=535–546 | doi=10.1016/j.molcel.2012.06.009 | pmc=3693578 | id= | pmid=22795129}} {{Cell-biology-stub}}2. ^{{cite journal |vauthors=Menon S, Dibble CC, Talbott G, Hoxhaj G, Valvezan AJ, Takahashi H, Cantley LC, Manning BD | title=Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome | journal= Cell | volume=156 | issue=4 | year=2014 | pages=771–785 | doi=10.1016/j.cell.2013.11.049 | pmc=403068 | id= | pmid=24529379}} 3. ^{{cite journal |vauthors=Harputlugil E, Hine C, Vargas D, Robertson L, Manning BD, Mitchell JR | title=The TSC complex is required for the benefits of dietary protein restriction on stress resistance in vivo | journal= Cell Reports | volume=8 | issue=4 | year=2014 | pages=1160–1170 | doi=10.1016/j.celrep.2014.07.018 | url=http://www.cell.com/cell-reports/abstract/S2211-1247(14)00585-3 | id= | pmid=25131199 | pmc=4260622}} 3 : Genes on human chromosome 9|Genes on human chromosome 16|Tumor suppressor genes |
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