Two for the Road may refer to:

• Two for the Road (film), a 1967 British comedy drama film
• "Two for the Road" (Lost), a 2006 episode of the American drama television series Lost
• Two for the Road (Herb Ellis and Joe Pass album), 1974
• Two for the Road (Carmen McRae and George Shearing album), 1980
• Two for the Road (Dave Grusin album), 1997
• Two for the Road (Larry Coryell & Steve Khan album), 1977
• "Two for the Road", a song by Bruce Springsteen from the box set Tracks

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