“UDP-glucuronate 5'-epimerase”的意思、由来-开放百科全书

词条

UDP-glucuronate 5'-epimerase

释义

References

{{enzyme
| Name = UDP-glucuronate 5'-epimerase
| EC_number = 5.1.3.12
| CAS_number = 37318-38-0
| IUBMB_EC_number = 5/1/3/12
| GO_code = 0050379
| image =
| width =
| caption =
}}

In enzymology, an UDP-glucuronate 5'-epimerase ({{EC number|5.1.3.12}}) is an enzyme that catalyzes the chemical reaction

UDP-glucuronate UDP-L-iduronate

Hence, this enzyme has one substrate, UDP-glucuronate, and one product, UDP-L-iduronate.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is UDP-glucuronate 5'-epimerase. Other names in common use include uridine diphosphoglucuronate 5'-epimerase, UDP-glucuronic acid 5'-epimerase, and C-5-uronosyl epimerase. This enzyme participates in nucleotide sugars metabolism. It employs one cofactor, NAD+.

References

{{cite journal | vauthors = Jacobson B, Davidson EA | title = Biosynthesis of uronic acids by skin enzymes. I. Uridine diphosphate-D-glucuronic acid-5-epimerase | journal = The Journal of Biological Chemistry | volume = 237 | pages = 638–42 | date = March 1962 | pmid = 14450717 }}

3 : EC 5.1.3|NADH-dependent enzymes|Enzymes of unknown structure

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