| 词条 | Valnemulin |
| 释义 |
| Verifiedfields = changed | verifiedrevid = 470628046 | IUPAC_name = (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyl- 5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro- 3a,9-propano-3aH-cyclopenta[8]annulen-8-yl- [(R)-2-(2-amino-3-methylbutanoylamino)-1,1-dimethtylethyl sulfanyl]acetate | image = Valnemulin.svg | width = 300 | tradename = Econor | Drugs.com = {{drugs.com|international|valnemulin}} | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = Veterinary use only | routes_of_administration = oral (in-feed) | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 101312-92-9 | ATCvet = yes | ATC_prefix = J01 | ATC_suffix = XQ02 | ATC_supplemental = | PubChem = 127791 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 8026591 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 2AHC415BQG | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 1688852 | chemical_formula = | C=31 | H=52 | N=2 | O=5 | S=1 | molecular_weight = 564.81 g/mol | smiles = O=C(NCC(SCC(=O)O[C@@H]2C[C@@](\\C=C)([C@@H](O)[C@@H]([C@]31[C@@H](C(=O)CC1)[C@@]2(C)[C@H](C)CC3)C)C)(C)C)[C@H](N)C(C)C | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C31H52N2O5S/c1-10-29(8)15-22(38-23(35)16-39-28(6,7)17-33-27(37)24(32)18(2)3)30(9)19(4)11-13-31(20(5)26(29)36)14-12-21(34)25(30)31/h10,18-20,22,24-26,36H,1,11-17,32H2,2-9H3,(H,33,37)/t19-,20+,22-,24-,25+,26+,29-,30+,31+/m1/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = LLYYNOVSVPBRGV-MVNKZKPCSA-N }}Valnemulin (trade name Econor) is a pleuromutilin antibiotic used to treat swine dysentery, ileitis, colitis and pneumonia. It is also used for the prevention of intestinal infections of swine.[1] Valnemulin has been observed to induce a rapid reduction of clinical symptoms of Mycoplasma bovis infection, and eliminate M. bovis from the lungs of calves.[2] References1. ^Econor: Product Profile {{Protein synthesis inhibitor antibiotics}}{{antibiotic-stub}}2. ^{{Cite journal| first1 = L.| last1 = Stipkovits | first2 = P.| first3 = M.| first4 = R.| first5 = T.| first6 = L.| title = The efficacy of valnemulin (Econor) in the control of disease caused by experimental infection of calves with| journal = Research in Veterinary Science| volume = 78| pages = 207–215| year = 2005 | doi = 10.1016/j.rvsc.2004.09.005| pmid = 15766939| last2 = Ripley| last3 = Tenk| last4 = Glávits| last5 = Molnár| last6 = Fodor| issue = 3}} 7 : Pleuromutilin antibiotics|Alcohols|Ketones|Isobutyrates|Thioethers|Carboxamides|Carboxylate esters |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。