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词条 Vesicular transport protein
释义

  1. Types

  2. Pathways

  3. See also

  4. References

A vesicular transport protein, or vesicular transporter, is a membrane protein that regulates or facilitates the movement of specific molecules across a vesicle's membrane.[1] As a result, vesicular transporters govern the concentration of molecules within a vesicle.

Types

Examples include:

  • Archain
  • ARFs
  • Clathrin
  • Caveolin
  • Dynamin and related proteins, such as the EHD protein family
  • Rab proteins
  • SNAREs
  • Vesicular transport adaptor proteins e.g. Sorting nexins
  • Synaptotagmin
  • TRAPP complex
  • Synaptophysin
  • Auxilin

Pathways

There are multiple pathways, each using its own coat and GTPase.[2]

  • COP 1 (Cytosolic coat protein complex ) : retrograde transport; Golgi ----> Endoplasmic reticulum
  • COP 2 (Cytosolic coat protein complex ) : anterograde transport; RER -----> cis-Golgi
  • Clathrin : trans-Golgi ----> Lysosomes, Plasma membrane ----> Endosomes (receptor-mediated endocytosis)

See also

  • Membrane transport protein
  • MeSH D12.776#MeSH D12.776.543.990 --- vesicular transport proteins

References

1. ^{{MeshName|Vesicular+Transport+Proteins}}
2. ^{{cite book|author=Yasushi Sako|title=Cell Signaling Reactions: Single-Molecular Kinetic Analysis|url=https://books.google.com/books?id=eM_fySpFdLkC&pg=PA168|accessdate=15 December 2010|date=1 October 2010|publisher=Springer|isbn=978-90-481-9863-4|pages=168–}}
{{Vesicular transport proteins}}{{membrane-protein-stub}}

2 : Vesicular transport proteins|Peripheral membrane proteins

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