“Vomilenine reductase”的意思、由来-开放百科全书

词条

Vomilenine reductase

释义

References

{{enzyme
| Name = vomilenine reductase
| EC_number = 1.5.1.32
| CAS_number = 462127-03-3
| IUBMB_EC_number = 1/5/1/32
| GO_code = 0050624
| image =
| width =
| caption =
}}

In enzymology, a vomilenine reductase ({{EC number|1.5.1.32}}) is an enzyme that catalyzes the chemical reaction

1,2-dihydrovomilenine + NADP⁺ vomilenine + NADPH + H⁺

Thus, the two substrates of this enzyme are 1,2-dihydrovomilenine and NADP⁺, whereas its 3 products are vomilenine, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 1,2-dihydrovomilenine:NADP+ oxidoreductase. This enzyme participates in indole and ipecac alkaloid biosynthesis.

References

{{cite journal |vauthors=von Schumann G, Gao S, Stockigt J | date = 2002 | title = Vomilenine reductase--a novel enzyme catalyzing a crucial step in the biosynthesis of the therapeutically applied antiarrhythmic alkaloid ajmaline | journal = Bioorg. Med. Chem. | volume = 10 | pages = 1913–8 | pmid = 11937349 | doi = 10.1016/S0968-0896(01)00435-7 | issue = 6 }}

3 : EC 1.5.1|NADPH-dependent enzymes|Enzymes of unknown structure

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