WISS may refer to:

• Western International School of Shanghai
• WISS (AM), a radio station (1100 AM) licensed to Berlin, Wisconsin, United States
  • WISS Trivia Contest, a long-running contest run by WISS.

• Isochorista ranulana
• Isochromodes
• Isochron
• Isochronic tones
• Isochronism
• Isochronous (band)
• Isochronous cyclotron
• Isochronous frequency
• Isochrysidales
• Isochrysis
• I Socialisti Italiani
• Isocitrate dehydrogenase (NADP+) kinase
• Isocitrate lyase family
• Isocitrate O-dihydroxycinnamoyltransferase
• Isoclinal
• Isoclinal Line
• Isoclinal Plane
• Isocline Hill
• Isoclinic
• Isoclinic Groups
• Isoclinic groups
• Isoclinic Lines
• Isoclinism
• Isoclinism of groups
• Isocoma acradenia