WS1 can refer to:

• Waardenburg syndrome, a genetic disorder
• Crown of Slaves, the 1st book in David Weber's Wages of Sin series.
• WS-1, (Weishi Rockets-1) a 302mm self-propelled multiple rocket launcher
• FA WSL 1, the top tier of the FA Women's Super League in English football
• WS1, a candidate phylum of bacteria

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