XPO may refer to:

• Frisky Dingo#Episodes
• Interpol
• XPO Logistics

• The ooze.com
• The Oozing Skull
• The Opal (annual)
• The Opal Deception
• The Opal (magazine)
• The Opals
• The OPANAL
• The Opaque Brotherhood
• Theo Parrish
• Theopaschite doctrine
• Theo Peckham
• Theo Peeters
• The Open Air Meeting
• The Open Boat
• The Open Boat and Other Tales of Adventure
• The Open Boat: A Tale Intended To Be After The Fact
• The Open Book
• The Open Disc
• The Open Door Children's Home
• The Open Door-EP
• The Open Door EP
• The Open Doors
• The OpenEnded Group
• The Opener
• The Opening (album)