| 词条 | Functional constipation |
| 释义 |
| name = Functional constipation | synonyms = Chronic idiopathic constipation | image = | width = | alt = | caption = | pronounce = | field = | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }} Functional constipation, known as chronic idiopathic constipation (CIC), is constipation that does not have a physical (anatomical) or physiological (hormonal or other body chemistry) cause. It may have a neurological, psychological or psychosomatic cause. A person with functional constipation may be healthy, yet has difficulty defecating. Symptoms and diagnosisChronic idiopathic constipation is similar to constipation-predominant irritable bowel syndrome (IBS-C); however, people with CIC do not have other symptoms of IBS, such as abdominal pain.[1] Diagnosing CIC can be difficult as other syndromes must be ruled out as there is no physiological cause for CIC. Doctors will typically look for other symptoms, such as blood in stool, weight loss, low blood count, or other symptoms. To be considered functional constipation, symptoms must be present at least a fourth of the time.[1] Possible causes are:
There is also possibility of presentation with other comorbid symptoms such as headache, especially in children.[2] TreatmentTreatment options appear similar and include prucalopride, lubiprostone, linaclotide, tegaserod, velusetrag, elobixibat, bisacodyl, sodium picosulphate[3], and most recently, plecanatide. ResearchA 2014 meta-analysis of three small trials evaluating probiotics showed a slight improvement in management of chronic idiopathic constipation, but well-designed studies are necessary to know the true efficacy of probiotics in treating this condition.[4] Children with functional constipation often claim to lack the sensation of the urge to defecate, and may be conditioned to avoid doing so due to a previous painful experience.[5] One retrospective study showed that these children did indeed have the urge to defecate using colonic manometry, and suggested behavioral modification as a treatment for functional constipation.[6] See also
References1. ^1 Americal College of Gastroenterology: Fuinctional Bowel Disorders {{DEFAULTSORT:Functional Constipation}}2. ^{{cite journal|title=Comorbidity of headache and functional constipation in children: a cross-sectional survey.|journal=Turk J Gastroenterol|pmid=25417610|doi=10.5152/tjg.2014.6183|volume=25|issue=5|year=2014|author=Inaloo S, Dehghani SM, Hashemi SM, Heydari M, Heydari ST|pages=508–11}} 3. ^{{cite journal|last1=Nelson|first1=AD|last2=Camilleri|first2=M|last3=Chirapongsathorn|first3=S|last4=Vijayvargiya|first4=P|last5=Valentin|first5=N|last6=Shin|first6=A|last7=Erwin|first7=PJ|last8=Wang|first8=Z|last9=Murad|first9=MH|title=Comparison of efficacy of pharmacological treatments for chronic idiopathic constipation: a systematic review and network meta-analysis.|journal=Gut|date=September 2017|volume=66|issue=9|pages=1611–1622|doi=10.1136/gutjnl-2016-311835|pmid=27287486}} 4. ^{{cite journal|last1=Ford|first1=Alexander C|last2=Quigley|first2=Eamonn M M|last3=Lacy|first3=Brian E|last4=Lembo|first4=Anthony J|last5=Saito|first5=Yuri A|last6=Schiller|first6=Lawrence R|last7=Soffer|first7=Edy E|last8=Spiegel|first8=Brennan M R|last9=Moayyedi|first9=Paul|title=Efficacy of Prebiotics, Probiotics, and Synbiotics in Irritable Bowel Syndrome and Chronic Idiopathic Constipation: Systematic Review and Meta-analysis|journal=The American Journal of Gastroenterology|volume=109|issue=10|year=2014|pages=1547–1561|issn=0002-9270|doi=10.1038/ajg.2014.202|pmid=25070051}} 5. ^{{cite journal|last=Fleisher|first=DR|title=Diagnosis and treatment of disorders of defecation in children|journal=Pediatric Annals|volume=5|issue=11|pages=71–101|date=November 1976|pmid=980548}} 6. ^{{cite journal|last=Firestone Baum|first=C|author2=John A |author3=Srinivasan K |author4=Harrison P |author5=Kolomensky A |author6=Monagas J |author7=Cocjin J |author8=Hyman PE |title=Colon manometry proves that perception of the urge to defecate is present in children with functional constipation who deny sensation|journal=Journal of Pediatric Gastroenterology and Nutrition|volume=56|issue=1|pages=19–22|date=January 2013|pmid= 22922371 |url=http://journals.lww.com/jpgn/Fulltext/2013/01000/Colon_Manometry_Proves_That_Perception_of_the_Urge.6.aspx|accessdate=2014-02-08 |doi=10.1097/MPG.0b013e31826f2740}} 1 : Constipation |
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