- First round
- First round replays
- Second round
- Second round replay
- Third round
- Fourth round
- Fifth round
- Semi-finals
- Final
- References
{{EngvarB|date=October 2014}}{{Use dmy dates|date=October 2014}}{{Infobox football tournament season
| title = 1880–81 FA Cup
| year =
| other_title =
| image =
| imagesize =
| caption =
| country = {{ENG}}
| num_teams = 62
| defending champions = Clapham Rovers
| champions = Old Carthusians
{{small|(1st title)}}
| runner-up = Old Etonians
| matches =
| goals =
| top goal scorer =
| player =
| prevseason = 1879–80
| nextseason = 1881–82
}}The 1880–81 Football Association Challenge Cup was the tenth staging of the FA Cup, England's oldest football tournament. Sixty-two teams entered, eight more than the previous season, although four of the sixty-two never played a match. First round| Home Club | Score | Away Club | Date |
|---|
| Darwen | 8–0 | Brigg | 13 November 1880 | | Reading | 5–1 | Hotspur | 13 November 1880 | | Sheffield | 5–4 | Blackburn Olympic | 30 October 1880 | | Royal Engineers | 0–0 | Remnants | 13 November 1880 | | Marlow | 6–0 | Clarence | 30 October 1880 | | Maidenhead | 1–1 | Old Harrovians | 13 November 1880 | | Clapham Rovers | 15–0 | Finchley | 13 November 1880 | | Upton Park | 8–1 | Mosquitos | 13 November 1880 | | Pilgrims | Walkover | Old Philberdians | | Swifts | 1–1 | Old Foresters | 6 November 1880 | | Herts Rangers | 6–0 | Barnes | 6 November 1880 | | Rochester | 1–2 | Dreadnought | 13 November 1880 | | Notts County | 4–4 | Derbyshire | 4 November 1880 | | Nottingham Forest | Walkover | Caius College | | Romford | 1–1 | Reading Minster | 13 November 1880 | | Grey Friars | 0–0 | Windsor Home Park | 13 November 1880 | | Brentwood | 0–10 | Old Etonians | 6 November 1880 | | West End | 1–0 | Hanover United | 6 November 1880 | | Blackburn Rovers | 6–2 | Providence | 30 October 1880 | | St Peter's Institute | 1–8 | Hendon | 6 November 1880 | | Aston Villa | 5–3 | Wednesbury Strollers | 30 October 1880 | | Stafford Road | 7–0 | Spilsby | 6 November 1880 | | Turton | 5–0 | Brigg Brittania | 16 October 1880 | | Old Carthusians | 7–0 | Saffron Walden Town | 23 October 1880 | | Acton | 1–1 | Kildare | 13 November 1880 | | Calthorpe | 1–2 | Grantham | 11 November 1880 | | Sheffield Wednesday | Walkover | Queen's Park | | Astley Bridge | 4–0 | Eagley | 30 October 1880 | | Weybridge Swallows | 3–1 | Henley | 13 November 1880 | | Reading Abbey | 1–0 | St Albans | 13 November 1880 | | Rangers (London) | Walkover | Wanderers |
First round replays| Home Club | Score | Away Club | Date |
|---|
| Remnants | 0–1 | Royal Engineers | 20 November 1880 | | Old Harrovians | 0–1 | Maidenhead | 20 November 1880 | | Old Foresters | 1–2 | Swifts | 20 November 1880 | | Derbyshire | 2–4 | Notts County | 27 November 1880 | | Romford | Walkover | Reading Minster | | Windsor Home Park | 1–3 | Grey Friars | 20 November 1880 | | Kildare | 0–5 | Acton | 20 November 1880 |
Second round| Home Club | Score | Away Club | Date |
|---|
| Grantham | 1–1 | Stafford Road | 11 December 1880 | | Reading | 0–1 | Swifts | 18 December 1880 | | Sheffield | 1–5 | Darwen | 18 December 1880 | | Royal Engineers | 1–0 | Pilgrims | 9 December 1880 | | Marlow | 4–0 | West End | 11 December 1880 | | Clapham Rovers | Bye | | Old Etonians | 2–0 | Hendon | 4 December 1880 | | Herts Rangers | Bye | | Notts County | Bye | | Nottingham Forest | 1–2 | Aston Villa | 4 December 1880 | | Romford | Bye | | Grey Friars | 1–0 | Maidenhead | 11 December 1880 | | Blackburn Rovers | 0–4 | Sheffield Wednesday | 18 December 1880 | | Old Carthusians | 5–1 | Dreadnought | 11 December 1880 | | Astley Bridge | 0–3 | Turton | 18 December 1880 | | Weybridge Swallows | 0–3 | Upton Park | 18 December 1880 | | Reading Abbey | 2–1 | Acton | 11 December 1880 | | Rangers (London) | Bye |
Second round replay| Home Club | Score | Away Club | Date |
|---|
| Stafford Road | 7–1 | Grantham | 16 December 1880 |
Third round| Home Club | Score | Away Club | Date |
|---|
| Darwen | Bye | | Royal Engineers | 6–0 | Rangers (London) | 9 February 1881 | | Marlow | Bye | | Clapham Rovers | 2–1 | Swifts | 8 January 1881 | | Upton Park | Bye | | Herts Rangers | 0–3 | Old Etonians | 5 February 1881 | | Notts County | 1–3 | Aston Villa | 12 February 1881 | | Romford | 2–0 | Reading Abbey | 12 February 1881 | | Grey Friars | Bye | | Stafford Road | Bye | | Turton | 0–2 | Sheffield Wednesday | 8 January 1881 |
Fourth round| Home Club | Score | Away Club | Date |
|---|
| Darwen | 5–2 | Sheffield Wednesday | 5 February 1881 | | Clapham Rovers | 5–4 | Upton Park | 12 February 1881 | | Old Etonians | 4–0 | Grey Friars | 19 February 1881 | | Romford | 2–1 | Marlow | 19 February 1881 | | Aston Villa | 2–3 | Stafford Road | 19 February 1881 | | Old Carthusians | 2–0 | Royal Engineers | 19 February 1881 |
Fifth round| Home Club | Score | Away Club | Date |
|---|
| Darwen | 15–0 | Romford | 5 March 1881 | | Stafford Road | 1–2 | Old Etonians | 19 March 1881 | | Old Carthusians | 3–1 | Clapham Rovers | 19 March 1881 |
Semi-finals| Home Club | Score | Away Club | Date |
|---|
| Old Etonians | Bye | | Old Carthusians | 4–1 | Darwen | 26 March 1881 |
Final{{Main|1881 FA Cup Final}}| Home Club | Score | Away Club | Date |
|---|
| Old Carthusians | 3–0 | Old Etonians | 9 April 1881 |
References{{FA Cup Seasons}}{{1880–81 in European football}}{{1880–81 in English football}}{{Portal bar|Association football}}{{DEFAULTSORT:Fa Cup 1880-81}} 3 : FA Cup seasons|1880–81 in English football|1880–81 domestic association football cups |