“(2,3-dihydroxybenzoyl)adenylate synthase”的意思、由来-开放百科全书

词条

(2,3-dihydroxybenzoyl)adenylate synthase

释义

References

{{enzyme
| Name = (2,3-dihydroxybenzoyl)adenylate synthase
| EC_number = 2.7.7.58
| CAS_number = 122332-73-4
| IUBMB_EC_number = 2/7/7/58
| GO_code = 0008668
| image =
| width =
| caption =
}}

In enzymology, a (2,3-dihydroxybenzoyl)adenylate synthase ({{EC number|2.7.7.58}}) is an enzyme that catalyzes the chemical reaction

ATP + 2,3-dihydroxybenzoate diphosphate + (2,3-dihydroxybenzoyl)adenylate

Thus, the two substrates of this enzyme are ATP and 2,3-dihydroxybenzoate, whereas its two products are diphosphate and (2,3-dihydroxybenzoyl)adenylate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ATP:2,3-dihydroxybenzoate adenylyltransferase. This enzyme is also called 2,3-dihydroxybenzoate-AMP ligase. This enzyme participates in biosynthesis of siderophore group nonribosomal.

References

{{cite journal |vauthors=Rusnak F, Faraci WS, Walsh CT | year = 1989 | title = Subcloning, expression, and purification of the enterobactin biosynthetic enzyme 2,3-dihydroxybenzoate-AMP ligase: demonstration of enzyme-bound (2,3-dihydroxybenzoyl)adenylate product | journal = Biochemistry | volume = 28 | pages = 6827–35 | pmid = 2531000 | doi = 10.1021/bi00443a008 | issue = 17 }}

{{Kinases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{DEFAULTSORT:2,3-dihydroxybenzoyladenylate synthase}}{{2.7-enzyme-stub}}

2 : EC 2.7.7|Enzymes of unknown structure

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