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词条 2-acylglycerol-3-phosphate O-acyltransferase
释义

  1. References

{{enzyme
| Name = 2-acylglycerol-3-phosphate O-acyltransferase
| EC_number = 2.3.1.52
| CAS_number = 51901-17-8
| IUBMB_EC_number = 2/3/1/52
| GO_code = 0047144
| image =
| width =
| caption =
}}

In enzymology, a 2-acylglycerol-3-phosphate O-acyltransferase ({{EC number|2.3.1.52}}) is an enzyme that catalyzes the chemical reaction

acyl-CoA + 2-acyl-sn-glycerol 3-phosphate CoA + 1,2-diacyl-sn-glycerol 3-phosphate

Thus, the two substrates of this enzyme are acyl-CoA and 2-acyl-sn-glycerol 3-phosphate, whereas its two products are CoA and 1,2-diacyl-sn-glycerol 3-phosphate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:2-acyl-sn-glycerol 3-phosphate O-acyltransferase. This enzyme is also called 2-acylglycerophosphate acyltransferase. This enzyme participates in glycerophospholipid metabolism.

References

  • {{cite journal |vauthors=Yamashita S, Hosaka K, Numa S | date = 1973 | title = Acyl-donor specificities of partially purified 1-acylglycerophosphate acyltransferase, 2-acylglycerophosphate acyltransferase and 1-acylglycerophosphorylcholine acyltransferase from rat-liver microsomes | journal = Eur. J. Biochem. | volume = 38 | pages = 25–31 | pmid = 4774123 | doi = 10.1111/j.1432-1033.1973.tb03028.x | issue = 1 }}
{{Acyltransferases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{2.3-enzyme-stub}}

2 : EC 2.3.1|Enzymes of unknown structure

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