| 词条 | 2CB-Ind |
| 释义 |
| Verifiedfields = changed | verifiedrevid = 477216871 | IUPAC_name = (5-bromo-4,7-dimethoxy-2,3-dihydro-1H-inden-1-yl)methanamine | image = 2CB-ind_structure.png | tradename = | legal_status = Uncontrolled | routes_of_administration = Oral | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 912342-23-5 | ATC_prefix = none | PubChem = 16086368 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 17245022 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 424890 | C=12 | H=16 | Br=1 | N=1 | O=2 | molecular_weight = 286.164 g/mol | smiles = COc1c(Br)cc(OC)c2c1CCC2CN | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C12H16BrNO2/c1-15-10-5-9(13)12(16-2)8-4-3-7(6-14)11(8)10/h5,7H,3-4,6,14H2,1-2H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = HCLPGYNQMVSQIM-UHFFFAOYSA-N }}2CB-Ind is a conformationally-restricted derivative of the phenethylamine hallucinogen 2C-B, discovered in 1974 by Alexander Shulgin. It acts as a moderately potent and selective agonist for the 5-HT2A and 5-HT2C receptors, but unlike the corresponding benzocyclobutene derivative TCB-2 which is considerably more potent than the parent compound 2C-B, 2CB-Ind is several times weaker, with racemic 2CB-Ind having a Ki of 47nM at the human 5-HT2A receptor, only slightly more potent than the mescaline analogue (R)-jimscaline.[1][2] Analogues and derivatives{{2C-B analogues and derivatives}}See also
References1. ^{{cite journal |last1= McLean |first1= TH |title= 1-Aminomethylbenzocycloalkanes: conformationally restricted hallucinogenic phenethylamine analogues as functionally selective 5-HT2A receptor agonists |journal= Journal of Medicinal Chemistry |volume= 49 |issue= 19 |pages= 5794–803 |year= 2006 |pmid= 16970404 |doi= 10.1021/jm060656o |display-authors=etal|citeseerx= 10.1.1.688.9849 }} {{Serotonergics}}{{DEFAULTSORT:2cb-Ind}}{{nervous-system-drug-stub}}2. ^{{Cite thesis |type=PhD. |title=Towards a biophysical understanding of hallucinogen action |url=http://proquest.umi.com/pqdlink?Ver=1&Exp=01-23-2014&FMT=7&DID=1417800971&RQT=309&attempt=1&cfc=1 |last=Braden |first=Michael Robert |year=2007 |publisher=Purdue University }} 3 : Bromoarenes|Phenol ethers|Indanes |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。