1. References

In enzymology, a 3-deoxyoctulosonase ({{EC number|3.2.1.144}}) is an enzyme that catalyzes the chemical reaction

3-deoxyoctulosonyl-lipopolysaccharide + H₂O 3-deoxyoctulosonic acid + lipopolysaccharide

Thus, the two substrates of this enzyme are 3-deoxyoctulosonyl-lipopolysaccharide and H₂O, whereas its two products are 3-deoxyoctulosonic acid and lipopolysaccharide.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is 3-deoxyoctulosonyl-lipopolysaccharide hydrolase. This enzyme is also called alpha-Kdo-ase.

References

• {{cite journal | vauthors = Li YT, Wang LX, Pavlova NV, Li SC, Lee YC | title = alpha-KDOase activity in oyster and synthesis of alpha- and beta-4-methylumbelliferyl ketosides of 3-deoxy-D-manno-octulosonic acid | journal = The Journal of Biological Chemistry | volume = 272 | issue = 42 | pages = 26419–24 | date = October 1997 | pmid = 9334217 | doi = 10.1074/jbc.272.42.26419 }}

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