| 词条 | 3-Fluoroethamphetamine |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 451560211 | IUPAC_name = N-ethyl-1-(3-fluorophenyl)propan-2-amine | image = 3-Fluoroethamphetamine.svg | tradename = | pregnancy_category = | legal_CA = Schedule I | legal_UK = Class A | legal_status = | routes_of_administration = | bioavailability = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = | ATC_prefix = none | ATC_suffix = | PubChem = 57458869 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 27050449 | C=11 | H=16 | F=1 | N=1 | molecular_weight = 181,25 g/mol | smiles = CC(CC1=CC(F)=CC=C1)NCC | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C11H16FN/c1-3-13-9(2)7-10-5-4-6-11(12)8-10/h4-6,8-9,13H,3,7H2,1-2H3 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = CKPWHLGHHXSVJI-UHFFFAOYSA-N }} 3-Fluoroethamphetamine (3-FEA) is a stimulant drug of the amphetamine class which acts as a releasing agent of the monoamine neurotransmitters norepinephrine, dopamine and serotonin. Compared to the unsubstituted ethylamphetamine, 3-fluoroethamphetamine is a weaker releaser of noradrenaline, but a stronger releaser of both dopamine and serotonin, and produced the strongest reinforcing effects in animal studies out of a range of 3-substituted ethamphetamine derivatives tested, despite not being the most potent dopamine releaser.[1][2][3][4] See also{{Colbegin}}
References1. ^Tessel RE, Woods JH. Structural relationship between meta-substituted N-ethylamphetamines and self-administration in rhesus monkeys. Pharmacologist 1974;16:142. {{Stimulants}}{{Phenethylamines}}{{DEFAULTSORT:Fluoroethamphetamine, 3-}}2. ^{{cite journal |author =Tessel RE |author2 =Woods JH |author3 =Counsell RE |author4 =Lu M |title=Structure-activity relationships between meta-substituted N-ethylamphetamines and locomotor activity in mice |journal=The Journal of Pharmacology and Experimental Therapeutics |volume=192 |issue=2 |pages=310–8 |date=February 1975 |pmid=1117418 |doi= |url=}} 3. ^{{cite journal |author =Tessel RE |author2 =Rutledge CO |title=Specificity of release of biogenic amines from isolated rat brain tissue as a function of the meta substituent of N-ethylamphetamine derivatives |journal=The Journal of Pharmacology and Experimental Therapeutics |volume=197 |issue=2 |pages=253–62 |date=May 1976 |pmid=1271279 |doi= |url=}} 4. ^{{cite journal |author =Tessel RE |author2 =Woods JH |title=meta Substituted N-ethylamphetamine self injection responding in the rhesus monkey: structure-activity relationships |journal=The Journal of Pharmacology and Experimental Therapeutics |volume=205 |issue=2 |pages=274–81 |date=May 1978 |pmid=417172 |doi= |url=}} 5 : Designer drugs|Fluoroarenes|Serotonin-norepinephrine-dopamine releasing agents|Stimulants|Substituted amphetamines |
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