释义 |
- References
- Further reading
{{Infobox_gene}}40S ribosomal protein S11 is a protein that in humans is encoded by the RPS11 gene.[1][2][3]Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17P family of ribosomal proteins. It is located in the cytoplasm. The gene product of the E. coli ortholog (ribosomal protein S17) is thought to be involved in the recognition of termination codons. This gene is co-transcribed with a small nucleolar RNA gene, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[3]References1. ^{{cite journal | vauthors = Feo S, Davies B, Fried M | title = The mapping of seven intron-containing ribosomal protein genes shows they are unlinked in the human genome | journal = Genomics | volume = 13 | issue = 1 | pages = 201–7 |date=Jun 1992 | pmid = 1577483 | pmc = | doi =10.1016/0888-7543(92)90221-D }} 2. ^{{cite journal | vauthors = Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC | title = A map of 75 human ribosomal protein genes | journal = Genome Res | volume = 8 | issue = 5 | pages = 509–23 |date=Aug 1998 | pmid = 9582194 | pmc = | doi = 10.1101/gr.8.5.509}} 3. ^1 {{cite web | title = Entrez Gene: RPS11 ribosomal protein S11| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6205| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Wool IG, Chan YL, Glück A |title=Structure and evolution of mammalian ribosomal proteins. |journal=Biochem. Cell Biol. |volume=73 |issue= 11–12 |pages= 933–47 |year= 1996 |pmid= 8722009 |doi=10.1139/o95-101 }}
- {{cite journal |vauthors=Ferrari S, Manfredini R, Tagliafico E, etal |title=Noncoordinated expression of S6, S11, and S14 ribosomal protein genes in leukemic blast cells |journal=Cancer Res. |volume=50 |issue= 18 |pages= 5825–8 |year= 1990 |pmid= 1697501 |doi= }}
- {{cite journal | vauthors=Lott JB, Mackie GA |title=Sequence of a cloned cDNA encoding human ribosomal protein S11 |journal=Nucleic Acids Res. |volume=16 |issue= 3 |pages= 1205 |year= 1988 |pmid= 3267208 |doi=10.1093/nar/16.3.1205 | pmc=334755 }}
- {{cite journal |vauthors=Vladimirov SN, Ivanov AV, Karpova GG, etal |title=Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry |journal=Eur. J. Biochem. |volume=239 |issue= 1 |pages= 144–9 |year= 1996 |pmid= 8706699 |doi=10.1111/j.1432-1033.1996.0144u.x }}
- {{cite journal | vauthors=Higa S, Yoshihama M, Tanaka T, Kenmochi N |title=Gene organization and sequence of the region containing the ribosomal protein genes RPL13A and RPS11 in the human genome and conserved features in the mouse genome |journal=Gene |volume=240 |issue= 2 |pages= 371–7 |year= 2000 |pmid= 10580157 |doi=10.1016/S0378-1119(99)00429-1 }}
- {{cite journal |vauthors=Andersen JS, Lyon CE, Fox AH, etal |title=Directed proteomic analysis of the human nucleolus |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=10.1016/S0960-9822(01)00650-9 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Bouwmeester T, Bauch A, Ruffner H, etal |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal | vauthors=Yu Y, Ji H, Doudna JA, Leary JA |title=Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes |journal=Protein Sci. |volume=14 |issue= 6 |pages= 1438–46 |year= 2005 |pmid= 15883184 |doi= 10.1110/ps.041293005 | pmc=2253395 }}
- {{cite journal |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein-protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 }}
{{refend}}{{GeneticTranslation}}{{Ribosome subunits}}{{gene-19-stub}} 1 : Ribosomal proteins |