| 释义 |
- Interactions
- References
- Further reading
{{Infobox_gene}}40S ribosomal protein S25 is a protein that in humans is encoded by the RPS25 gene.[1][2]Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S25E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[2]InteractionsRPS25 has been shown to interact with CDC5L.[3] References1. ^{{cite journal |vauthors=Li ML, Latoud C, Center MS | title = Cloning and sequencing a cDNA encoding human ribosomal protein S25 | journal = Gene | volume = 107 | issue = 2 | pages = 329–33 |date=January 1992 | pmid = 1748303 | pmc = | doi = 10.1016/0378-1119(91)90335-9}}
2. ^1 {{cite web | title = Entrez Gene: RPS25 ribosomal protein S25| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6230| accessdate = }}
3. ^{{cite journal |last=Ajuh |first=P |authorlink= |author2=Kuster B |author3=Panov K |author4=Zomerdijk J C |author5=Mann M |author6=Lamond A I |date=December 2000 |title=Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry |journal=EMBO J. |volume=19 |issue=23 |pages=6569–81 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 11101529 |doi = 10.1093/emboj/19.23.6569 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=305846 }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Wool IG, Chan YL, Glück A |title=Structure and evolution of mammalian ribosomal proteins. |journal=Biochem. Cell Biol. |volume=73 |issue= 11-12 |pages= 933–47 |year= 1996 |pmid= 8722009 |doi=10.1139/o95-101 }}
- {{cite journal |vauthors=Li M, Center MS |title=Regulation of ribosomal protein S25 in HL60 cells isolated for resistance to adriamycin. |journal=FEBS Lett. |volume=298 |issue= 2-3 |pages= 142–4 |year= 1992 |pmid= 1544436 |doi=10.1016/0014-5793(92)80041-E }}
- {{cite journal |vauthors=Marion MJ, Marion C |title=Ribosomal proteins S2, S6, S10, S14, S15 and S25 are localized on the surface of mammalian 40 S subunits and stabilize their conformation. A study with immobilized trypsin. |journal=FEBS Lett. |volume=232 |issue= 2 |pages= 281–5 |year= 1988 |pmid= 3378620 |doi=10.1016/0014-5793(88)80753-1 }}
- {{cite journal |vauthors=Kato S, Sekine S, Oh SW, etal |title=Construction of a human full-length cDNA bank. |journal=Gene |volume=150 |issue= 2 |pages= 243–50 |year= 1995 |pmid= 7821789 |doi=10.1016/0378-1119(94)90433-2 }}
- {{cite journal |vauthors=Imai T, Sudo K, Miwa T |title=Assignment of the human ribosomal protein S25 gene (RPS25) to chromosome 11q23.3 by sequence analysis of the marker D11S456. |journal=Genomics |volume=20 |issue= 1 |pages= 142–3 |year= 1994 |pmid= 8020948 |doi= 10.1006/geno.1994.1145 }}
- {{cite journal |vauthors=Miwa T, Sudo K, Nakamura Y, Imai T |title=Fifty sequenced-tagged sites on human chromosome 11. |journal=Genomics |volume=17 |issue= 1 |pages= 211–4 |year= 1993 |pmid= 8406452 |doi= 10.1006/geno.1993.1304 }}
- {{cite journal |vauthors=Vladimirov SN, Ivanov AV, Karpova GG, etal |title=Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry. |journal=Eur. J. Biochem. |volume=239 |issue= 1 |pages= 144–9 |year= 1996 |pmid= 8706699 |doi=10.1111/j.1432-1033.1996.0144u.x }}
- {{cite journal |vauthors=Kenmochi N, Kawaguchi T, Rozen S, etal |title=A map of 75 human ribosomal protein genes. |journal=Genome Res. |volume=8 |issue= 5 |pages= 509–23 |year= 1998 |pmid= 9582194 |doi= 10.1101/gr.8.5.509}}
- {{cite journal |vauthors=Kubota S, Copeland TD, Pomerantz RJ |title=Nuclear and nucleolar targeting of human ribosomal protein S25: common features shared with HIV-1 regulatory proteins. |journal=Oncogene |volume=18 |issue= 7 |pages= 1503–14 |year= 1999 |pmid= 10050887 |doi= 10.1038/sj.onc.1202429 }}
- {{cite journal |vauthors=Ajuh P, Kuster B, Panov K, etal |title=Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. |journal=EMBO J. |volume=19 |issue= 23 |pages= 6569–81 |year= 2001 |pmid= 11101529 |doi= 10.1093/emboj/19.23.6569 | pmc=305846 }}
- {{cite journal |vauthors=Yoshihama M, Uechi T, Asakawa S, etal |title=The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. |journal=Genome Res. |volume=12 |issue= 3 |pages= 379–90 |year= 2002 |pmid= 11875025 |doi= 10.1101/gr.214202 | pmc=155282 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M }}
- {{cite journal |vauthors=Lehner B, Sanderson CM |title=A protein interaction framework for human mRNA degradation. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004 | pmc=442147 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Yu Y, Ji H, Doudna JA, Leary JA |title=Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes. |journal=Protein Sci. |volume=14 |issue= 6 |pages= 1438–46 |year= 2005 |pmid= 15883184 |doi= 10.1110/ps.041293005 | pmc=2253395 }}
- {{cite journal |vauthors=Stelzl U, Worm U, Lalowski M, etal |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029 }}
{{refend}}{{GeneticTranslation}}{{Ribosome subunits}}{{gene-11-stub}} 1 : Ribosomal proteins |