| 词条 | 5-Aminoimidazole ribotide |
| 释义 |
| Verifiedfields = changed | verifiedrevid = 477224023 | ImageFile=Aminoimidazole ribotide.svg | ImageSize= | IUPACName=[5-(5-aminoimidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate | OtherNames=AIR, [5-(5-amino-1-imidazolyl)-3,4-dihydroxy-2-tetrahydrofuranyl]methyl dihydrogen phosphate |Section1={{Chembox Identifiers | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 141854 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C8H14N3O7P/c9-5-1-10-3-11(5)8-7(13)6(12)4(18-8)2-17-19(14,15)16/h1,3-4,6-8,12-13H,2,9H2,(H2,14,15,16)/t4-,6-,7-,8-/m1/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = PDACUKOKVHBVHJ-XVFCMESISA-N | CASNo_Ref = {{cascite|changed|??}} | CASNo=25635-88-5 | ChEBI_Ref = {{ebicite|changed|EBI}} | ChEBI=138560 | KEGG_Ref = {{keggcite|changed|kegg}} | KEGG=C03373 | PubChem=153 | SMILES=O=P(O)(O)OC[C@H]2O[C@@H](n1cncc1N)[C@H](O)[C@@H]2O | MeSHName=aminoimidazole+ribotide |Section2={{Chembox Properties | Formula=C8H14N3O7P | MolarMass=295.186 g/mol | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }}5'-Phosphoribosyl-5-aminoimidazole (or aminoimidazole ribotide) is an intermediate in the formation of purines. Thus, it is an intermediate in the adenine pathway, and is synthesized from 5'-phosphoribosylformylglycinamidine by AIR synthetase.[1] See also
References1. ^{{Cite journal | doi=10.1021/ja00168a039|title = Nonenzymatic synthesis and properties of 5-aminoimidazole ribonucleotide (AIR). Synthesis of specifically 15N-labeled 5-aminoimidazole ribonucleoside (AIRs) derivatives| journal=Journal of the American Chemical Society| volume=112| issue=12| pages=4891–4897|year = 1990|last1 = Bhat|first1 = Balkrishen| last2=Groziak| first2=Michael P.| last3=Leonard| first3=Nelson J.}} {{Nucleotide metabolism intermediates}}{{DEFAULTSORT:Aminoimidazole ribotide, 5-}}{{biochemistry-stub}} 1 : Nucleotides |
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