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词条 5-Benzyloxytryptamine
释义

  1. See also

  2. References

{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 477224082
| IUPAC_name = 2-(5-phenylmethoxy-1H-indol-3-yl)ethanamine
| image = 5-benzyloxytryptamine.png
| tradename =
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 20776-45-8
| PubChem = 89576
| IUPHAR_ligand = 265
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 80845
| C=17 | H=18 | N=2 | O=1
| molecular_weight = 266.34 g/mol
| smiles = NCCC1=CNC2=CC=C(OCC3=CC=CC=C3)C=C21
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C17H18N2O/c18-9-8-14-11-19-17-7-6-15(10-16(14)17)20-12-13-4-2-1-3-5-13/h1-7,10-11,19H,8-9,12,18H2
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = WKPDXBXNJWWWGQ-UHFFFAOYSA-N
}}5-Benzyloxytryptamine (5-BT), is a tryptamine derivative which acts as an agonist at the 5-HT1D, 5-HT2 and 5-HT6 serotonin receptors.[1][2][3][4]

See also

  • 5-Carboxamidotryptamine
  • 5-Methoxytryptamine
  • BW-723C86
  • Sumatriptan

References

1. ^{{cite journal |vauthors =Lyon RA, Titeler M, Seggel MR, Glennon RA |title=Indolealkylamine analogs share 5-HT2 binding characteristics with phenylalkylamine hallucinogens |journal=European Journal of Pharmacology |volume=145 |issue=3 |pages=291–7 |date=January 1988 |pmid=3350047 |doi= 10.1016/0014-2999(88)90432-3|url=}}
2. ^{{cite journal |vauthors =Peroutka SJ, McCarthy BG, Guan XM |title=5-benzyloxytryptamine: a relatively selective 5-hydroxytryptamine 1D/1B agent |journal=Life Sciences |volume=49 |issue=6 |pages=409–18 |year=1991 |pmid=1650872 |doi= 10.1016/0024-3205(91)90582-V|url=}}
3. ^{{cite journal |vauthors =Cohen ML, Schenck K, Nelson D, Robertson DW |title=Sumatriptan and 5-benzyloxytryptamine: contractility of two 5-HT1D receptor ligands in canine saphenous veins |journal=European Journal of Pharmacology |volume=211 |issue=1 |pages=43–6 |date=January 1992 |pmid=1319907 |doi= 10.1016/0014-2999(92)90260-B|url=}}
4. ^{{cite journal |vauthors =Boess FG, Monsma FJ, Carolo C, Meyer V, Rudler A, Zwingelstein C, Sleight AJ |title=Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells |journal=Neuropharmacology |volume=36 |issue=4–5 |pages=713–20 |year=1997 |pmid=9225298 |doi= 10.1016/S0028-3908(97)00019-1|url=}}
{{Serotonergics}}{{Tryptamines}}{{DEFAULTSORT:Benzyloxytryptamine, 5-}}{{nervous-system-drug-stub}}

3 : Serotonin receptor agonists|Tryptamines|Phenol ethers

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