| 释义 |
- References
- Further reading
{{Infobox_gene}}60S ribosomal protein L17 is a protein that in humans is encoded by the RPL17 gene.[1][2][3]Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as RPL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. Two alternative splice variants have been observed, each encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[3]References1. ^{{cite journal | vauthors = Mager DL, Freeman JD | title = A human gene related to the ribosomal protein L23 gene of Halobacterium marismortui | journal = Nucleic Acids Res | volume = 18 | issue = 17 | pages = 5301 |date=Oct 1990 | pmid = 2402465 | pmc = 332174 | doi =10.1093/nar/18.17.5301 }}
2. ^{{cite journal | vauthors = Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC | title = A map of 75 human ribosomal protein genes | journal = Genome Res | volume = 8 | issue = 5 | pages = 509–23 |date=Aug 1998 | pmid = 9582194 | pmc = | doi = 10.1101/gr.8.5.509}}
3. ^1 {{cite web | title = Entrez Gene: RPL17 ribosomal protein L17| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6139| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Wool IG, Chan YL, Glück A |title=Structure and evolution of mammalian ribosomal proteins. |journal=Biochem. Cell Biol. |volume=73 |issue= 11–12 |pages= 933–47 |year= 1996 |pmid= 8722009 |doi=10.1139/o95-101 }}
- {{cite journal |vauthors=Andersen JS, Lyon CE, Fox AH, etal |title=Directed proteomic analysis of the human nucleolus |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=10.1016/S0960-9822(01)00650-9 }}
- {{cite journal |vauthors=Yoshihama M, Uechi T, Asakawa S, etal |title=The human ribosomal protein genes: sequencing and comparative analysis of 73 genes |journal=Genome Res. |volume=12 |issue= 3 |pages= 379–90 |year= 2002 |pmid= 11875025 |doi= 10.1101/gr.214202 | pmc=155282 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Matsuda A, Suzuki Y, Honda G, etal |title=Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways |journal=Oncogene |volume=22 |issue= 21 |pages= 3307–18 |year= 2003 |pmid= 12761501 |doi= 10.1038/sj.onc.1206406 }}
- {{cite journal |vauthors=Odintsova TI, Müller EC, Ivanov AV, etal |title=Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing |journal=J. Protein Chem. |volume=22 |issue= 3 |pages= 249–58 |year= 2004 |pmid= 12962325 |doi=10.1023/A:1025068419698 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Andersen JS, Lam YW, Leung AK, etal |title=Nucleolar proteome dynamics |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207 }}
{{refend}}{{GeneticTranslation}}{{Ribosome subunits}}{{protein-stub}} 1 : Ribosomal proteins |