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词条 6-aminohexanoate-cyclic-dimer hydrolase
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{{enzyme
| Name = 6-aminohexanoate-cyclic-dimer hydrolase
| EC_number = 3.5.2.12
| CAS_number = 60976-29-6
| IUBMB_EC_number = 3/5/2/12
| GO_code = 0019874
| image =
| width =
| caption =
}}

In enzymology, a 6-aminohexanoate-cyclic-dimer hydrolase ({{EC number|3.5.2.12}}) is an enzyme that catalyzes the chemical reaction

1,8-diazacyclotetradecane-2,9-dione + H2O N-(6-aminohexanoyl)-6-aminohexanoate

Thus, the two substrates of this enzyme are 1,8-diazacyclotetradecane-2,9-dione and H2O, whereas its product is N-(6-aminohexanoyl)-6-aminohexanoate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is 1,8-diazacyclotetradecane-2,9-dione lactamhydrolase.

References

  • {{cite journal | vauthors = Kinoshita S, Negoro S, Muramatsu M, Bisaria VS, Sawada S, Okada H | year = 1977 | title = 6-Aminohexanoic acid cyclic dimer hydrolase. A new cyclic amide hydrolase produced by Achromobacter guttatus KI74 | journal = Eur. J. Biochem. | volume = 80 | pages = 489–95 | pmid = 923591 | doi = 10.1111/j.1432-1033.1977.tb11904.x | issue = 2 }}

External links

  • {{Commonscatinline}}
{{Carbon-nitrogen non-peptide hydrolases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{3.5-enzyme-stub}}

2 : EC 3.5.2|Enzymes of unknown structure

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