| 词条 | 6-Fluoro-DMT |
| 释义 |
| verifiedrevid = 458134580 | IUPAC_name = 2-(6-fluoro-1H-indol-3-yl)-N,N-dimethyl-ethanamine | image = 6-Fluoro-DMT skeletal.svg | tradename = | pregnancy_category = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 26286731 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C12H15FN2/c1-15(2)6-5-9-8-14-12-7-10(13)3-4-11(9)12/h3-4,7-8,14H,5-6H2,1-2H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = DZXZPVGWRZCXDH-UHFFFAOYSA-N | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 1511-31-5 | ATC_prefix = none | ATC_suffix = | PubChem = | C=12 | H=15 | F=1 | N=2 | molecular_weight = 206.26 g/mol | smiles =CN(CCC1=CNC2=C1C=CC(F)=C2)C }} 6-Fluoro-N,N-dimethyltryptamine (6-Fluoro-DMT) is a synthetic drug of the tryptamine chemical class. PharmacologyBinding profile6-Fluoro-DMT possess affinity for the 5-HT1A (392.6 nM), 5-HT1B (217.7 nM), 5-HT1D (55.4 nM), 5-HT1E (460.8 nM), 5-HT2A (866 nM), 5-HT2B (29.8 nM), 5-HT2C (674.2 nM), 5-HT5A (960.5 nM), 5-HT6 (25.6 nM), 5-HT7 (40.8 nM), D1 (547.3 nM), D2 (610.4 nM), D3 (866.8 nM), D4 (1,454 nM), D5 (6,291 nM), α1A-adrenergic (173.3 nM), α2B-adrenergic (295.5 nM), α2C-adrenergic (148.8 nM), H1 (46.6 nM), H2 (925.4 nM), I1 (898.4 nM), 1 (6,892 nM), and 2 (7,128 nM) receptors, as well as the SERT (144.6 nM).[1] It has low/negligible (> 10,000 nM) affinity for the 5-HT3, α1B-adrenergic, α2A-adrenergic, β1-adrenergic, β2-adrenergic, H3, H4, and M1-M5 receptors, as well as the DAT and NET.[1] It has not been screened at 5-HT1F, 5-HT4, α1D-adrenergic, β3-adrenergic, or VMAT1/VMAT2. See also
References1. ^1 {{cite journal | author = Ray TS | title = Psychedelics and the human receptorome |journal = PLoS ONE | volume = 5 | issue = 2 | pages = e9019 | year = 2010 | pmid = 20126400 | doi = 10.1371/journal.pone.0009019 | url = | pmc=2814854}} External links
1 : Tryptamines |
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