词条 | 7-ACA |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 477226392 | Name = 7-Aminocephalosporanic acid | ImageFile = 7-ACA.svg | ImageFile_Ref = {{chemboximage|correct|??}} | ImageSize = 244 | ImageName = Partially condensed, stereo, skeletal formula of 7-aminocephalosporanic acid | ImageFile2 = 7-ACA-3D-balls.png | SystematicName = 3-(Acetyloxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | OtherNames = 7-Aminocephalosporinic acid |Section1={{Chembox Identifiers | Abbreviations = 7-ACA | CASNo = 957-68-6 | CASNo_Ref = {{cascite|correct|CAS}} | PubChem = 483168 | ChemSpiderID = 390087 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | EINECS = 213-485-0 | KEGG = C07756 | KEGG_Ref = {{keggcite|correct|kegg}} | MeSHName = 7-Aminocephalosporanic+acid | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = 2255 | ChEMBL = 1161449 | ChEMBL_Ref = {{ebicite|correct|EBI}} | Beilstein = 622637, 8919572 | 3DMet = B02205 | SMILES = O=C2N1/C(=C(\\CS[C@@H]1[C@@H]2N)COC(=O)C)C(=O)O | StdInChI = 1S/C10H12N2O5S/c1-4(13)17-2-5-3-18-9-6(11)8(14)12(9)7(5)10(15)16/h6,9H,2-3,11H2,1H3,(H,15,16)/t6-,9-/m1/s1 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = HSHGZXNAXBPPDL-HZGVNTEJSA-N | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} }} |Section2={{Chembox Properties | C=10 | H=12 | N=2 | S=1 | O=5 | MeltingPtC = 300 | MeltingPt_ref = [1] | LogP = -1.87 | pKa = 2.59 | pKb = 11.41 }} |Section3={{Chembox Hazards | GHSPictograms = {{GHS health hazard}} | GHSSignalWord = Danger | HPhrases = {{H-phrases|317|334}} | PPhrases = {{P-phrases|261|280|342+311}} }} }}7-ACA (7-aminocephalosporanic acid) is the core chemical structure for the synthesis of cephalosporin antibiotics and intermediates. It can be obtained by chemoenzymatic hydrolysis of cephalosporin C.[2][3] See also
References1. ^7-ACA at Chemblink {{Organic-compound-stub}}2. ^{{cite journal | journal = World Journal of Microbiology & Biotechnology | volume = 26 | issue = 1 | pages = 145–152 | year = 2010 | doi = 10.1007/s11274-009-0153-9 | title = Single-pot conversion of cephalosporin C to 7-aminocephalosporanic acid in the absence of hydrogen peroxide | last1 = Tan | first1 = Qiang | last2 = Zhang | first2 = Yewang | last3 = Song | first3 = Qingxun | last4 = Wei | first4 = Dongzhi}} 3. ^{{cite journal | journal = Enzyme and Microbial Technology | volume = 39 | issue = 5 | pages = 1166–1172 | year = 2006 | doi = 10.1016/j.enzmictec.2006.02.028 | title = Single-pot conversion of cephalosporin C to 7-aminocephalosporanic acid using cell-bound and support-bound enzymes | last1 = Tan | first1 = Qiang | last2 = Song | first2 = Qingxun | last3 = Wei | first3 = Dongzhi}} 3 : Cephalosporin antibiotics|Acetate esters|Sulfur heterocycles |
随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。