词条 | Acetarsol |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 477238724 | ImageFile = Acetarsol.svg | ImageFile_Ref = {{chemboximage|correct|??}} | ImageSize = 244 | ImageName = Kekulé, skeletal formula of acetarsol | PIN = (3-Acetamido-4-hydroxyphenyl)arsonic acid | OtherNames = 3-Acetamido-4-hydroxyphenylarsonic acid{{Citation needed|date = June 2011}} Acetarsol |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|changed|??}} | CASNo = 97-44-9 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 1330792 | PubChem = 1985 | ChemSpiderID = 1908 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | UNII = 806529YU1N | UNII_Ref = {{fdacite|correct|FDA}} | EINECS = 202-582-3 | UNNumber = 3465 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D07110 | MeSHName = Acetarsol | SMILES = CC(=O)Nc1cc(ccc1O)[As](O)(O)=O | SMILES1 = CC(=O)NC1=CC(=CC=C1O)[As](O)(O)=O | StdInChI = 1S/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15) | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | InChI = 1/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15) | StdInChIKey = ODFJOVXVLFUVNQ-UHFFFAOYSA-N | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | InChIKey = ODFJOVXVLFUVNQ-UHFFFAOYAX}} |Section2={{Chembox Properties | C=8|As=1|N=1|H=10|O=5 | MolarMass = 275.0903 g mol−1 }} |Section6={{Chembox Pharmacology | ATCCode_prefix = A07 | ATCCode_suffix = AX02 | ATC_Supplemental = {{ATC|G01|AB01}}, {{ATC|P01|CD02}}, {{ATC|P51|AD05}} }} |Section7={{Chembox Hazards | GHSPictograms = {{GHS skull and crossbones}} {{GHS environment}} | GHSSignalWord = Danger | HPhrases = {{H-phrases|301|331|410}} | PPhrases = {{P-phrases|261|273|301+310|311|501}} }} }}Acetarsol is an anti-infective.[1] It was first discovered in 1921 at Pasteur Institute by Ernest Fourneau, and sold under the brand name Stovarsol (fourneau is the French word for stove).[2][3] It has been given in suppositories.[4] Acetarsol can be used to make Arsthinol, & presumably Acetarsone also. References1. ^{{cite journal |vauthors=Chen MY, Smith NA, Fox EF, Bingham JS, Barlow D |title=Acetarsol pessaries in the treatment of metronidazole resistant Trichomonas vaginalis |journal=Int J STD AIDS |volume=10 |issue=4 |pages=277–80 |date=April 1999 |pmid=12035784 |doi= 10.1258/0956462991913943|url=http://ijsa.rsmjournals.com/cgi/pmidlookup?view=long&pmid=12035784}} {{Antidiarrheals, intestinal anti-inflammatory/anti-infective agents}}{{Agents against leishmaniasis and trypanosomiasis}}{{Gastrointestinal-drug-stub}}{{Antiinfective-drug-stub}}{{Genito-urinary-drug-stub}}2. ^Éric Fouassier, Ces poisons qui guérissent, oct. 1996, p. 5. 3. ^Traité de chimie organique, sous la direction de Victor Grignard, Paul Baud, vol. 22, Masson, 1959, p. 1127-1130. 4. ^{{cite journal |vauthors=Gionchetti P, Rizzello F, Morselli C, Campieri M |title=Review article: problematic proctitis and distal colitis |journal=Aliment. Pharmacol. Ther. |volume=20 Suppl 4 |issue= |pages=93–6 |date=October 2004 |pmid=15352902 |doi=10.1111/j.1365-2036.2004.02049.x |url=http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0269-2813&date=2004&volume=20&issue=&spage=93 |archive-url=https://archive.is/20130105054057/http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0269-2813&date=2004&volume=20&issue=&spage=93 |dead-url=yes |archive-date=2013-01-05 }} 4 : Antiprotozoal agents|Acetanilides|Arsonic acids|Phenols |
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