词条 | Acetoxolone |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 457801722 | ImageFile=Acetoxolone.png | IUPACName=(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-acetyloxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid | OtherNames=Acetylglycyrrhetinic acid |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|changed|??}} | CASNo=6277-14-1 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 207413 | PubChem=94320 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = CWW961Q19K | SMILES=CC(=O)O[C@H]1CC[C@]2([C@H](C1(C)C)CC[C@@]3([C@@H]2C(=O)C=C4[C@]3(CC[C@@]5([C@H]4C[C@@](CC5)(C)C(=O)O)C)C)C)C | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 85123 | InChI = 1/C32H48O5/c1-19(33)37-24-10-11-30(6)23(27(24,2)3)9-12-32(8)25(30)22(34)17-20-21-18-29(5,26(35)36)14-13-28(21,4)15-16-31(20,32)7/h17,21,23-25H,9-16,18H2,1-8H3,(H,35,36)/t21-,23-,24-,25+,28+,29-,30-,31+,32+/m0/s1 | InChIKey = FTQDJVZNPJRVPG-XWEVEMRCBD | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C32H48O5/c1-19(33)37-24-10-11-30(6)23(27(24,2)3)9-12-32(8)25(30)22(34)17-20-21-18-29(5,26(35)36)14-13-28(21,4)15-16-31(20,32)7/h17,21,23-25H,9-16,18H2,1-8H3,(H,35,36)/t21-,23-,24-,25+,28+,29-,30-,31+,32+/m0/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = FTQDJVZNPJRVPG-XWEVEMRCSA-N |Section2={{Chembox Properties | C=32 | H=48 | O=5 | MolarMass=512.72 g/mol | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section6={{Chembox Pharmacology | ATCCode_prefix = A02 | ATCCode_suffix = BX09 }} |Section7={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }} Acetoxolone is a drug used for peptic ulcer and gastroesophageal reflux disease. It is an acetyl derivative of glycyrrhetinic acid. See also
References{{Drugs for peptic ulcer and GORD}}{{Glucocorticoidics}}{{gastrointestinal-drug-stub}} 6 : 11β-Hydroxysteroid dehydrogenase inhibitors|Drugs acting on the gastrointestinal system and metabolism|Triterpenes|Carboxylic acids|Ketones|Acetate esters |
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