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词条 Acetoxolone
释义

  1. See also

  2. References

{{unreferenced|date=September 2015}}{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 457801722
| ImageFile=Acetoxolone.png
| IUPACName=(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-acetyloxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
| OtherNames=Acetylglycyrrhetinic acid
|Section1={{Chembox Identifiers
| CASNo_Ref = {{cascite|changed|??}}
| CASNo=6277-14-1
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 207413
| PubChem=94320
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = CWW961Q19K
| SMILES=CC(=O)O[C@H]1CC[C@]2([C@H](C1(C)C)CC[C@@]3([C@@H]2C(=O)C=C4[C@]3(CC[C@@]5([C@H]4C[C@@](CC5)(C)C(=O)O)C)C)C)C
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 85123
| InChI = 1/C32H48O5/c1-19(33)37-24-10-11-30(6)23(27(24,2)3)9-12-32(8)25(30)22(34)17-20-21-18-29(5,26(35)36)14-13-28(21,4)15-16-31(20,32)7/h17,21,23-25H,9-16,18H2,1-8H3,(H,35,36)/t21-,23-,24-,25+,28+,29-,30-,31+,32+/m0/s1
| InChIKey = FTQDJVZNPJRVPG-XWEVEMRCBD
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C32H48O5/c1-19(33)37-24-10-11-30(6)23(27(24,2)3)9-12-32(8)25(30)22(34)17-20-21-18-29(5,26(35)36)14-13-28(21,4)15-16-31(20,32)7/h17,21,23-25H,9-16,18H2,1-8H3,(H,35,36)/t21-,23-,24-,25+,28+,29-,30-,31+,32+/m0/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = FTQDJVZNPJRVPG-XWEVEMRCSA-N
|Section2={{Chembox Properties
| C=32 | H=48 | O=5
| MolarMass=512.72 g/mol
| Appearance=
| Density=
| MeltingPt=
| BoilingPt=
| Solubility=
|Section6={{Chembox Pharmacology
| ATCCode_prefix = A02
| ATCCode_suffix = BX09
}}
|Section7={{Chembox Hazards
| MainHazards=
| FlashPt=
| AutoignitionPt =
}}

Acetoxolone is a drug used for peptic ulcer and gastroesophageal reflux disease. It is an acetyl derivative of glycyrrhetinic acid.

See also

  • Carbenoxolone
  • Enoxolone

References

{{Drugs for peptic ulcer and GORD}}{{Glucocorticoidics}}{{gastrointestinal-drug-stub}}

6 : 11β-Hydroxysteroid dehydrogenase inhibitors|Drugs acting on the gastrointestinal system and metabolism|Triterpenes|Carboxylic acids|Ketones|Acetate esters

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