| 释义 |
- References
- External links
- Further reading
{{Infobox_gene}}Acyl-CoA Synthetase, Bubblegum Family, member 1 (ACSBG1) is an enzyme that in humans is encoded by the ACSBG1 gene.[1][2][3]The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis.[3] The conversion of long chain fatty acids into long chain acyl-CoAs in mice is catalysed by ACSBG1.[4] References1. ^{{cite journal | vauthors = Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro | journal = DNA Res | volume = 5 | issue = 3 | pages = 169–76 |date=Dec 1998 | pmid = 9734811 | pmc = | doi =10.1093/dnares/5.3.169 }}
2. ^{{cite journal | vauthors = Steinberg SJ, Morgenthaler J, Heinzer AK, Smith KD, Watkins PA | title = Very long-chain acyl-CoA synthetases. Human "bubblegum" represents a new family of proteins capable of activating very long-chain fatty acids | journal = J Biol Chem | volume = 275 | issue = 45 | pages = 35162–9 |date=Nov 2000 | pmid = 10954726 | pmc = | doi = 10.1074/jbc.M006403200 }}
3. ^1 {{cite web | title = Entrez Gene: ACSBG1 acyl-CoA synthetase bubblegum family member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23205| accessdate = }}
4. ^{{cite journal | title=Novel acyl-CoA synthetase in adrenoleukodystrophy target tissues. | vauthors=Moriya-Sato A | journal=Biochem Biophys Res Commun |date=Dec 2000 | volume=279 | issue=1 | pages=62–8. | doi=10.1006/bbrc.2000.3897 | pmid=11112418|display-authors=etal}}
External links- {{UCSC gene info|ACSBG1}}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Andersson B, Wentland MA, Ricafrente JY |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 |display-authors=etal}}
- {{cite journal | vauthors=Yu W, Andersson B, Worley KC |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi= 10.1101/gr.7.4.353| pmc=139146 |display-authors=etal}}
- {{cite journal | vauthors=Moriya-Sato A, Hida A, Inagawa-Ogashiwa M |title=Novel acyl-CoA synthetase in adrenoleukodystrophy target tissues. |journal=Biochem. Biophys. Res. Commun. |volume=279 |issue= 1 |pages= 62–8 |year= 2001 |pmid= 11112418 |doi= 10.1006/bbrc.2000.3897 |display-authors=etal}}
- {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
- {{cite journal | vauthors=Pei Z, Oey NA, Zuidervaart MM |title=The acyl-CoA synthetase "bubblegum" (lipidosin): further characterization and role in neuronal fatty acid beta-oxidation.. |journal=J. Biol. Chem. |volume=278 |issue= 47 |pages= 47070–8 |year= 2004 |pmid= 12975357 |doi= 10.1074/jbc.M310075200 |display-authors=etal}}
- {{cite journal | vauthors=Fraisl P, Forss-Petter S, Zigman M, Berger J |title=Murine bubblegum orthologue is a microsomal very long-chain acyl-CoA synthetase. |journal=Biochem. J. |volume=377 |issue= Pt 1 |pages= 85–93 |year= 2004 |pmid= 14516277 |doi= 10.1042/BJ20031062 | pmc=1223850 }}
- {{cite journal | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
- {{cite journal | vauthors=Asheuer M, Bieche I, Laurendeau I |title=Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy. |journal=Hum. Mol. Genet. |volume=14 |issue= 10 |pages= 1293–303 |year= 2005 |pmid= 15800013 |doi= 10.1093/hmg/ddi140 |display-authors=etal}}
{{refend}}{{gene-15-stub}} 1 : Human proteins |