| 释义 |
- Function
- References
- External links
- Further reading
{{Infobox_gene}}Actin-related protein 3B also known as ARP3-beta is a protein that in humans is encoded by the ACTR3B gene.[1] Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms.[1] Function This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility.[1] References 1. ^1 2 {{cite web | title = Entrez Gene: ACTR3B ARP3 actin-related protein 3 homolog B (yeast)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57180| accessdate = }}
External links- {{UCSC gene info|ACTR3B}}
Further reading {{refbegin | 2}}- {{cite journal | vauthors = Machesky LM, Gould KL | title = The Arp2/3 complex: a multifunctional actin organizer | journal = Current Opinion in Cell Biology | volume = 11 | issue = 1 | pages = 117–21 | date = Feb 1999 | pmid = 10047519 | doi = 10.1016/S0955-0674(99)80014-3 }}
- {{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Molecular Systems Biology | volume = 3 | issue = 1 | pages = 89 | year = 2007 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 }}
- {{cite journal | vauthors = Shindo-Okada N, Iigo M | title = Expression of the Arp11 gene suppresses the tumorigenicity of PC-14 human lung adenocarcinoma cells | journal = Biochemical and Biophysical Research Communications | volume = 312 | issue = 4 | pages = 889–96 | date = Dec 2003 | pmid = 14651955 | doi = 10.1016/j.bbrc.2003.10.200 }}
- {{cite journal | vauthors = Shindo-Okada N, Shimizu K | title = Isolation of a novel actin-related gene expressed in low-metastatic PC-14 human lung adenocarcinoma | journal = Biochemical and Biophysical Research Communications | volume = 280 | issue = 1 | pages = 61–7 | date = Jan 2001 | pmid = 11162478 | doi = 10.1006/bbrc.2000.4059 }}
- {{cite journal | vauthors = Jay P, Bergé-Lefranc JL, Massacrier A, Roessler E, Wallis D, Muenke M, Gastaldi M, Taviaux S, Cau P, Berta P | title = ARP3beta, the gene encoding a new human actin-related protein, is alternatively spliced and predominantly expressed in brain neuronal cells | journal = European Journal of Biochemistry / FEBS | volume = 267 | issue = 10 | pages = 2921–8 | date = May 2000 | pmid = 10806390 | doi = 10.1046/j.1432-1327.2000.01306.x }}
{{refend}}{{PDB Gallery|geneid=57180}}{{NLM content}}{{gene-7-stub}} 2 : Human proteins|Genes on human chromosome 7 |