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词条 Glucoraphanin
释义

  1. References

{{Chembox
| ImageFile = Glucoraphanin.png
| ImageSize = 200px
| ImageCaption = Potassium salt of glucoraphanin
| IUPACName = 1-S-[(1E)-5-(methylsulfinyl)-N-(sulfonatooxy)pentanimidoyl]-1-thio-β-D-glucopyranose
| OtherNames = Glucorafanin; 4-Methylsulfinylbutyl glucosinolate
|Section1={{Chembox Identifiers
| CASNo = 21414-41-5
| CASNo_Ref = {{cascite|correct|CAS}}
| PubChem = 656556
| ChemSpiderID = 570930
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 79311
| SMILES = [O-]S(=O)(=O)ON=C(S[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)CO)CCCCS(=O)C
| InChI = 1/C12H23NO10S3/c1-25(18)5-3-2-4-8(13-23-26(19,20)21)24-12-11(17)10(16)9(15)7(6-14)22-12/h7,9-12,14-17H,2-6H2,1H3,(H,19,20,21)/p-1/t7-,9-,10+,11-,12+,25?/m1/s1
| InChIKey = GMMLNKINDDUDCF-XQSZSTCOBC
| StdInChI = 1S/C12H23NO10S3/c1-25(18)5-3-2-4-8(13-23-26(19,20)21)24-12-11(17)10(16)9(15)7(6-14)22-12/h7,9-12,14-17H,2-6H2,1H3,(H,19,20,21)/p-1/t7-,9-,10+,11-,12+,25?/m1/s1
| StdInChIKey = GMMLNKINDDUDCF-SISVVIKZSA-M
|Section2={{Chembox Properties
| C=12 | H=23 | N=1 | O=10 | S=3
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}Glucoraphanin is a glucosinolate found in broccoli,[1] cauliflower,[2] and mustard.[3]

Glucoraphanin is converted to Sulforaphane by the enzyme Myrosinase[4]. In plants sulforaphane deters insect predators and act as a selective antibiotic[5], in humans sulforaphane consumption has been linked with a decrease in Neurodegenerative[6] and Cardiovascular Disease[7].

Due to the potential health benefits, a variety of broccoli has been bred to contain 2-3 times more glucoraphanin than standard broccoli.[8]

References

1. ^{{Cite journal | doi = 10.1111/j.1753-4887.2012.00532.x| pmid = 23110644| title = Novel concepts of broccoli sulforaphanes and disease: Induction of phase II antioxidant and detoxification enzymes by enhanced-glucoraphanin broccoli| journal = Nutrition Reviews| volume = 70| issue = 11| pages = 654–65| year = 2012| last1 = James | first1 = D. | last2 = Devaraj | first2 = S. | last3 = Bellur | first3 = P. | last4 = Lakkanna | first4 = S. | last5 = Vicini | first5 = J. | last6 = Boddupalli | first6 = S. }}
2. ^{{cite journal |author1=Jeffery, E. H. |author2=Brown, A. F. |author3=Kurilich, A. C. |author4=Keck, A. S. |author5=Matusheski, N. |author6=Klein, B. P. |author7=Juvik, J. A. | title = Variation in content of bioactive components in broccoli | journal = Journal of Food Composition and Analysis | year = 2003 | volume = 16 | issue = 3 | pages = 323–330 | doi = 10.1016/S0889-1575(03)00045-0}}
3. ^{{Cite journal | doi = 10.11002/kjfp.2015.22.4.553| title = Sinigrin content of different parts of Dolsan leaf mustard| journal = Korean Journal of Food Preservation| volume = 22| issue = 4| pages = 553–558| year = 2015| last1 = Oh | first1 = K. | last2 = SangOk | first2 = K. | last3 = Rak| first3 = C. }}
4. ^{{cite journal |last1=Cuomo |first1=Valentina |last2=Luciano |first2=Fernando B. |last3=Meca |first3=Giuseppe |last4=Ritieni |first4=Alberto |last5=Mañes |first5=Jordi |title=Bioaccessibility of glucoraphanin from broccoli using an gastrointestinal digestion model |journal=CyTA - Journal of Food |date=26 November 2014 |volume=13 |issue=3 |pages=361–365 |doi=10.1080/19476337.2014.984337}}
5. ^{{cite journal |last1=Fahey |first1=Jed W. |last2=Holtzclaw |first2=W. David |last3=Wehage |first3=Scott L. |last4=Wade |first4=Kristina L. |last5=Stephenson |first5=Katherine K. |last6=Talalay |first6=Paul |last7=Mukhopadhyay |first7=Partha |title=Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase |journal=PLOS ONE |date=2 November 2015 |volume=10 |issue=11 |pages=e0140963 |doi=10.1371/journal.pone.0140963|pmc=4629881 }}
6. ^{{cite journal |last1=Tarozzi |first1=Andrea |last2=Angeloni |first2=Cristina |last3=Malaguti |first3=Marco |last4=Morroni |first4=Fabiana |last5=Hrelia |first5=Silvana |last6=Hrelia |first6=Patrizia |title=Sulforaphane as a Potential Protective Phytochemical against Neurodegenerative Diseases |journal=Oxidative Medicine and Cellular Longevity |date=2013 |volume=2013 |pages=1–10 |doi=10.1155/2013/415078}}
7. ^{{cite journal |last1=Bai |first1=Yang |last2=Wang |first2=Xiaolu |last3=Zhao |first3=Song |last4=Ma |first4=Chunye |last5=Cui |first5=Jiuwei |last6=Zheng |first6=Yang |title=Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation |journal=Oxidative Medicine and Cellular Longevity |date=2015 |volume=2015 |pages=1–13 |doi=10.1155/2015/407580}}
8. ^{{cite news|last=Cheng|first=Maria|title=UK scientists grow super broccoli|url=http://articles.boston.com/2011-10-26/lifestyle/30324726_1_broccoli-glucoraphanin-vegetables-and-cancer|accessdate=10 November 2011|newspaper=Associated Press|date=October 26, 2011}}

2 : Glucosinolates|Brassica oleracea

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