词条 | AL-1095 |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 477235632 | IUPAC_name = 2-(1-phenyl-1-(p-chlorophenyl)methyl)-3-hydroxyquinuclidine | image = AL-1095_structure.png | tradename = | pregnancy_category = | legal_status = Unscheduled | routes_of_administration = | bioavailability = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 54549-19-8 | ATC_prefix = none | ATC_suffix = | PubChem = 3041659 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 2304906 | C=20 | H=22 | Cl=1 | N=1 | O=1 | molecular_weight = 327.139 g/mol | smiles = OC(C1CCN2CC1)C2C(C3=CC=C(Cl)C=C3)C4=CC=CC=C4 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C20H22ClNO/c21-17-8-6-15(7-9-17)18(14-4-2-1-3-5-14)19-20(23)16-10-12-22(19)13-11-16/h1-9,16,18-20,23H,10-13H2/t18?,19-,20+/m0/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = JXCMZYHEZWCLOD-NRRUETGQSA-N }}AL-1095,[1] developed by Aldrich{{cn|date=October 2017}}, is a centrally acting stimulant drug with comparable effects to amphetamine,[2] developed by Bristol in the 1970s.[3] See also
References1. ^US Patent 3506673 -2-(4'HALO)-BENZHYDRYL-3-QUINUCLIDINOLS {{Stimulants}}{{nervous-system-drug-stub}}2. ^{{cite book |author1=Hedblom, P. |author2=Grinspoon, L. | title = The Speed Culture: Amphetamine Use and Abuse in America | publisher = Harvard University Press | location = Cambridge | year = 1975 | page = 50 | isbn = 0-674-83192-6 | url = https://books.google.com/books?id=LyStWcRD6QIC&lpg=PA50&pg=PA50 }} 3. ^{{ cite journal | title = Quinuclidine Chemistry. 3. β-cis-2-(4'-Chlorobenzhydryl)-3-quinuclidinol, a New Central Nervous System Stimulant. Importance of the Benzhydryl Configuration |author1=Warawa, E. J. |author2=Mueller, N. J. |author3=Gylys, J. A. | journal = Journal of Medicinal Chemistry | year = 1975 | volume = 18 | issue = 1 | pages = 71–74 | pmid = 803245 | doi = 10.1021/jm00235a016 }} 4 : Stimulants|Quinuclidines|Chloroarenes|Alcohols |
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