词条 | Alan R. Saltiel |
释义 |
During his doctorate studies in biochemistry at the University of North Carolina, Saltiel worked on thyroid-stimulating hormone and its relationship to thyroid cancer. As a post-doctoral fellow under Pedro Cuatrecasas in the Wellcome Research Labs, he began investigating insulin. He was Distinguished Research Fellow and Senior Director of the Department of Cell Biology at Parke-Davis Pharmaceutical Research Division (now Pfizer Global Research). In addition to having published more than 260 research papers, Saltiel holds 16 patents and has extensive experience with the FDA's testing and approval process for new drugs. Saltiel's lab researches signaling pathways in insulin action.[5] Such research is aimed at identifying the various ways in which problems with the insulin signaling pathway trigger diabetes.[6] Researchers in the lab have also uncovered new hormone signaling pathways and the role that proteins and genes play in this process.[7] These discoveries may reveal how the insulin-glucose balance necessary for the survival of the cell is lost due to obesity in those with diabetes.[8][9] Awards and achievementsSaltiel has received many awards over the course of his career, including the Rosalyn Yalow Research and Development Award from the American Diabetes Association, Hirschl Award, The John Jacob Abel Award from ASPET and The Goodman and Gilman Award, also from ASPET.[10] He is a member of the Institute of Medicine and fellow of the American Association for the Advancement of Science. His work is often cited in biochemistry literature;[11] with more than 35,000 citations as of February 2014, he ranks among the most influential scientists in biology and biochemistry in the world.[12] His true dream is to star for the New York Knicks.[13] References1. ^{{Cite web |url=http://www.medicineatmichigan.org/magazine/2005/fall/limelight/saltiel.asp |title=Alan Saltiel Elected to Institute of Medicine-Medicine at Michigan Fall 2005 |access-date=2007-12-17 |archive-url=https://web.archive.org/web/20080223134605/http://www.medicineatmichigan.org/magazine/2005/fall/limelight/saltiel.asp |archive-date=2008-02-23 |dead-url=yes |df= }} 2. ^{{Cite web |url= http://141.211.144.29/facultyresearch/labs/saltiel/affiliations |title=Saltiel Lab - Affiliations {{!}} Life Sciences at Michigan here |access-date=2007-12-17 |archive-url= https://web.archive.org/web/20110529061144/http://141.211.144.29/facultyresearch/labs/saltiel/affiliations |archive-date=2011-05-29 |dead-url=yes |df= }} 3. ^University of Michigan 4. ^{{Cite web |url= http://lsi.umich.edu/facultyresearch/labs/saltiel/picv |title= Saltiel Lab - Faculty - Curriculum Vitae {{!}} Life Sciences at Michigan here |accessdate=2007-12-17 |archive-url= https://web.archive.org/web/20081119034641/http://lsi.umich.edu/facultyresearch/labs/saltiel/picv |archive-date=2008-11-19 |dead-url=yes |df= }} 5. ^[https://www.nytimes.com/2007/10/16/health/16diab.html?pagewanted=2&_r=1&ei=5070&en=b247f3211ed791a5&ex=1193112000&emc=eta1 In Diabetes, a Complex of Causes - New York Times] 6. ^{{Cite web |url=http://www.med.umich.edu/brehm/research/saltiel.htm |title=University of Michigan: Diabetes at U of M |access-date=2007-12-17 |archive-url=https://web.archive.org/web/20080124102113/http://www.med.umich.edu/brehm/research/saltiel.htm |archive-date=2008-01-24 |dead-url=yes |df= }} 7. ^{{Cite web |url=http://www.med.umich.edu/brehm/research/saltiel.htm |title=University of Michigan: Diabetes at U of M |access-date=2007-12-17 |archive-url=https://web.archive.org/web/20080124102113/http://www.med.umich.edu/brehm/research/saltiel.htm |archive-date=2008-01-24 |dead-url=yes |df= }} 8. ^{{Cite web |url=http://www.medicineatmichigan.org/magazine/2005/fall/limelight/saltiel.asp |title=Alan Saltiel Elected to Institute of Medicine-Medicine at Michigan Fall 2005 |access-date=2007-12-17 |archive-url=https://web.archive.org/web/20080223134605/http://www.medicineatmichigan.org/magazine/2005/fall/limelight/saltiel.asp |archive-date=2008-02-23 |dead-url=yes |df= }} 9. ^{{Cite web |url=http://www.med.umich.edu/brehm/research/saltiel.htm |title=University of Michigan: Diabetes at U of M |access-date=2007-12-17 |archive-url=https://web.archive.org/web/20080124102113/http://www.med.umich.edu/brehm/research/saltiel.htm |archive-date=2008-01-24 |dead-url=yes |df= }} 10. ^Access to articles : Nature Reviews Drug Discovery 11. ^Access to articles : Nature Reviews Drug Discovery 12. ^Highly Cited Research 13. ^http://www.in-cites.com/scientists/AlanSaltiel.html External links
6 : Year of birth missing (living people)|Living people|Duke University alumni|University of North Carolina at Chapel Hill alumni|Life Sciences Institute, University of Michigan|University of Michigan faculty |
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