Alix is a surname. Notable people with the surname include:

• Adolfo Alix, Jr. (born 1978), Filipino screenwriter
• Gabriel Alix (1930–1998), Haitian painter
• May Alix (1902–1983), American jazz vocalist
• Pierre-Michel Alix (1762–1817), French engraver
• Alberto García-Alix (1956-) Spanish photographer of La Movida Madrileña
• Antonio García-Alix (1852-1911), Spanish Attorney and Politician, Minister for Public Instruction and Fine Arts, then for Finance, Government.
• José Alix-Alix (1912-1988), Spanish Physician, specializing in Tuberculosis therapy from the pre-antibiotic era, pioneer of Thoracic Surgery.

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