词条 | Allopurinol hypersensitivity syndrome |
释义 |
| name = Allopurinol hypersensitivity syndrome | synonyms = | image = Allopurinol structure.png | caption = Allopurinol | pronounce = | field = | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }}Allopurinol hypersensitivity syndrome typically occurs in persons with preexisting kidney failure.[1]{{rp|119}} Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption[1]{{rp|119}} or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal necrolysis.[2] See also
References1. ^1 James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. {{ISBN|0-7216-2921-0}}. 2. ^{{cite journal | vauthors = Wang CW, Dao RL, Chung WH | title = Immunopathogenesis and risk factors for allopurinol severe cutaneous adverse reactions | journal = Current Opinion in Allergy and Clinical Immunology | volume = 16 | issue = 4 | pages = 339–45 | date = August 2016 | pmid = 27362322 | doi = 10.1097/ACI.0000000000000286 | url = }} External links{{Medical resources| DiseasesDB = | ICD10 = {{ICD10|Y|54|8|y|40}} | ICD9 = {{ICD9|E944.7}} | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = }}{{External causes of morbidity and mortality}}{{Cutaneous-condition-stub}} 2 : Drug eruptions|Syndromes |
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