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词条 Almagate
释义

  1. Adverse effects

  2. References

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| verifiedrevid = 443400546
| IUPAC_name =
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| Drugs.com = {{drugs.com|international|almagate}}
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| legal_status =
| routes_of_administration = Oral
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number = 66827-12-1
| ATC_prefix = A02
| ATC_suffix = AD03
| PubChem = 71749
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 64792
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 568Z59H7ZJ
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D02821
| chemical_formula = Al2Mg6(OH)14(CO3)2 · 4 H2O
| molecular_weight = 314.99 g/mol
| smiles = [Al+3].[Mg+2].[Mg+2].[Mg+2].[OH-].[OH-].[OH-].[O-]C([O-])=O.[OH-].[OH-].[OH-].[OH-].O.O
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/CH2O3.Al.3Mg.9H2O/c2-1(3)4;;;;;;;;;;;;;/h(H2,2,3,4);;;;;9*1H2/q;+3;3*+2;;;;;;;;;/p-9
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = MTEOMEWVDVPTNN-UHFFFAOYSA-E
}}Almagate (trade name Almax) is an aluminium- and magnesium-containing antacid. It was first described in 1984.[1][2]

Adverse effects

Almagate is well tolerated. In a clinical trial, the most common adverse effects were diarrhea and nausea.[3]

References

1. ^{{Cite journal| pmid = 6548918| year = 1984| author = Moragues| month = | first = J. B.| title = Characterization of a new crystalline synthetic gastric antacid, almagate| volume = 34| issue = 10A| pages = 1346–1349| issn = 0004-4172| journal = Arzneimittel-Forschung| url = http://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+21645-51-2| format = Free full text}}
2. ^{{Cite journal | pmid = 6439224 | year = 1984| author = Beneyto | month = | first = J. F. B. | title = Evaluation of a new antacid, almagate | volume = 34 | issue = 10A | pages = 1350–1354 | issn = 0004-4172 | journal = Arzneimittel-Forschung | url = http://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+21645-51-2 | format = Free full text}}
3. ^{{Cite journal| pmid = 6548926| year = 1984| author = Suau| month = | first = A. D.| title = Treatment of gastric pyrosis with almagate in patients with and without endoscopically demonstrable duodenal ulcer. A multicentre clinical trial| volume = 34| issue = 10A| pages = 1380–1383| issn = 0004-4172| journal = Arzneimittel-Forschung| url = http://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+21645-51-2| format = Free full text| last2 = Dominguez Martin| first2 = A| last3 = Ferrando Cucarella| first3 = J| last4 = Juncosa Iglesias| first4 = L| last5 = Muñoz Benitez| first5 = J| last6 = Nieto Calvet| first6 = M| last7 = Pérez Gieb| first7 = J| last8 = Pérez Mota| first8 = A| last9 = Pineda Garcia| first9 = A| last10 = Rodriguez Sanchez| first10 = E}}
{{Antacids}}{{gastrointestinal-drug-stub}}

3 : Antacids|Aluminium compounds|Magnesium compounds

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