词条 | Altizide |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 456682206 | ImageFile = Altizide.svg | ImageSize = 250 | IUPACName = (3R)-3-[(Allylsulfanyl)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide | OtherNames = {{unbulleted list|Althiazide|CB 8093|P 1779|Altizidum}} | Section1 = {{Chembox Identifiers | UNII_Ref = {{fdacite|correct|FDA}} | UNII = GI8CB72B0D | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 599870 | PubChem = 6604323 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 5036613 | SMILES = O=S(=O)(c1c(Cl)cc2c(c1)S(=O)(=O)N[C@@H](N2)CSC\\C=C)N | InChI = 1/C11H14ClN3O4S3/c1-2-3-20-6-11-14-8-4-7(12)9(21(13,16)17)5-10(8)22(18,19)15-11/h2,4-5,11,14-15H,1,3,6H2,(H2,13,16,17)/t11-/m1/s1 | InChIKey = VGLGVJVUHYTIIU-LLVKDONJBT | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C11H14ClN3O4S3/c1-2-3-20-6-11-14-8-4-7(12)9(21(13,16)17)5-10(8)22(18,19)15-11/h2,4-5,11,14-15H,1,3,6H2,(H2,13,16,17)/t11-/m1/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = VGLGVJVUHYTIIU-LLVKDONJSA-N | CASNo_Ref = {{cascite|changed|??}} | CASNo = 5588-16-9 | PubChem2 = 2122 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D02838 | SMILES2 = C=CCSCC1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl | Section2 = {{Chembox Properties | Formula = C11H14ClN3O4S3 | MolarMass = 383.89456 | Appearance = | Density = 1.502 g/mL | MeltingPt = | BoilingPtC = 625.8 | Solubility = | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}Altizide is a thiazide diuretic. In combination with spironolactone it is sold under the brand name of Aldactacine and Aldactazine by Pfizer and other names by other companies.[1][2] References1. ^{{cite web|title=Altizide|url=https://www.drugs.com/international/altizide.html|website=drugs.com}} {{Diuretics}}{{cardiovascular-drug-stub}}2. ^{{cite journal|title=Clinical update: spironolactone and altizide as monotherapy in systemic hypertension|journal=The American Journal of Cardiology|volume=65|issue=23|pages=20K–23K|pmid=2191585|year=1990|author1=Dueymes|first1=J. M}} 5 : Allyl compounds|Benzothiadiazines|Chloroarenes|Diuretics|Thioethers |
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