| 释义 |
- Interactions
- References
- External links
- Further reading
{{Infobox_gene}}Anaphase-promoting complex subunit 5 is an enzyme that in humans is encoded by the ANAPC5 gene.[1][2]The anaphase-promoting complex (APC) consists of at least 8 protein subunits, including APC5, CDC27 (APC3; MIM 116946), CDC16 (APC6; MIM 603461), and CDC23 (APC8; MIM 603462).[supplied by OMIM][2] InteractionsANAPC5 has been shown to interact with ANAPC1,[3][4] ANAPC4,[3] CDC27[3][5][6] and PABPC1.[5] References1. ^{{cite journal | vauthors = Yu H, Peters JM, King RW, Page AM, Hieter P, Kirschner MW | title = Identification of a cullin homology region in a subunit of the anaphase-promoting complex | journal = Science | volume = 279 | issue = 5354 | pages = 1219–22 |date=March 1998 | pmid = 9469815 | pmc = | doi =10.1126/science.279.5354.1219 | bibcode =1998Sci...279.1219Y }}
2. ^1 {{cite web | title = Entrez Gene: ANAPC5 anaphase promoting complex subunit 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51433| accessdate = }}
3. ^1 2 {{cite journal |last=Vodermaier |first=Hartmut C |last2=Gieffers |first2=Christian |last3=Maurer-Stroh |first3=Sebastian |last4=Eisenhaber |first4=Frank |last5=Peters |first5=Jan-Michael |date=September 2003 |title=TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1 |journal=Curr. Biol. |volume=13 |issue=17 |pages=1459–68 | issn = 0960-9822| pmid = 12956947 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1016/S0960-9822(03)00581-5 }}
4. ^{{cite journal |last=Sumara |first=I |author2=Vorlaufer E |author3=Gieffers C |author4=Peters B H |author5=Peters J M |date=November 2000 |title=Characterization of Vertebrate Cohesin Complexes and Their Regulation in Prophase |journal=J. Cell Biol. |volume=151 |issue=4 |pages=749–62 | issn = 0021-9525| pmid = 11076961 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1083/jcb.151.4.749 |pmc=2169443 }}
5. ^1 {{cite journal |last=Koloteva-Levine |first=Nadejda |last2=Pinchasi |first2=Dalia |last3=Pereman |first3=Idan |last4=Zur |first4=Amit |last5=Brandeis |first5=Michael |last6=Elroy-Stein |first6=Orna |date=May 2004 |title=The Apc5 Subunit of the Anaphase-Promoting Complex/Cyclosome Interacts with Poly(A) Binding Protein and Represses Internal Ribosome Entry Site-Mediated Translation |journal=Mol. Cell. Biol. |volume=24 |issue=9 |pages=3577–87 | issn = 0270-7306| pmid = 15082755 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1128/MCB.24.9.3577-3587.2004 |pmc=387753 }}
6. ^{{cite journal |last=Gmachl |first=M |author2=Gieffers C |author3=Podtelejnikov A V |author4=Mann M |author5=Peters J M |date=August 2000 |title=The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue=16 |pages=8973–8 | issn = 0027-8424| pmid = 10922056 | bibcode =2000PNAS...97.8973G | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1073/pnas.97.16.8973 |pmc=16806 }}
External links- {{UCSC gene info|ANAPC5}}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Grossberger R, Gieffers C, Zachariae W |title=Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex |journal=J. Biol. Chem. |volume=274 |issue= 20 |pages= 14500–7 |year= 1999 |pmid= 10318877 |doi=10.1074/jbc.274.20.14500 |display-authors=etal}}
- {{cite journal | vauthors=Gieffers C, Peters BH, Kramer ER |title=Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 20 |pages= 11317–22 |year= 1999 |pmid= 10500174 |doi=10.1073/pnas.96.20.11317 | pmc=18031 |display-authors=etal|bibcode=1999PNAS...9611317G}}
- {{cite journal | vauthors=Gmachl M, Gieffers C, Podtelejnikov AV |title=The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 16 |pages= 8973–8 |year= 2000 |pmid= 10922056 |doi=10.1073/pnas.97.16.8973 | pmc=16806 |display-authors=etal|bibcode=2000PNAS...97.8973G}}
- {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal|bibcode=2002PNAS...9916899M }}
- {{cite journal | vauthors=Vodermaier HC, Gieffers C, Maurer-Stroh S |title=TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1 |journal=Curr. Biol. |volume=13 |issue= 17 |pages= 1459–68 |year= 2004 |pmid= 12956947 |doi=10.1016/S0960-9822(03)00581-5 |display-authors=etal}}
- {{cite journal | vauthors=Kraft C, Herzog F, Gieffers C |title=Mitotic regulation of the human anaphase-promoting complex by phosphorylation |journal=EMBO J. |volume=22 |issue= 24 |pages= 6598–609 |year= 2004 |pmid= 14657031 |doi= 10.1093/emboj/cdg627 | pmc=291822 |display-authors=etal}}
- {{cite journal | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
- {{cite journal | vauthors=Koloteva-Levine N, Pinchasi D, Pereman I |title=The Apc5 Subunit of the Anaphase-Promoting Complex/Cyclosome Interacts with Poly(A) Binding Protein and Represses Internal Ribosome Entry Site-Mediated Translation |journal=Mol. Cell. Biol. |volume=24 |issue= 9 |pages= 3577–87 |year= 2004 |pmid= 15082755 |doi=10.1128/MCB.24.9.3577-3587.2004 | pmc=387753 |display-authors=etal}}
- {{cite journal | vauthors=Beausoleil SA, Jedrychowski M, Schwartz D |title=Large-scale characterization of HeLa cell nuclear phosphoproteins |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101 | pmc=514446 |display-authors=etal|bibcode=2004PNAS..10112130B }}
- {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
- {{cite journal | vauthors=Barrios-Rodiles M, Brown KR, Ozdamar B |title=High-throughput mapping of a dynamic signaling network in mammalian cells |journal=Science |volume=307 |issue= 5715 |pages= 1621–5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776 |display-authors=etal|bibcode=2005Sci...307.1621B }}
- {{cite journal | vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal|bibcode=2005Natur.437.1173R }}
- {{cite journal | vauthors=Turnell AS, Stewart GS, Grand RJ |title=The APC/C and CBP/p300 cooperate to regulate transcription and cell-cycle progression |journal=Nature |volume=438 |issue= 7068 |pages= 690–5 |year= 2005 |pmid= 16319895 |doi= 10.1038/nature04151 |display-authors=etal|bibcode=2005Natur.438..690T }}
{{refend}}{{gene-12-stub}} |