| 词条 | Anisodine |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 457811074 | IUPAC_name = 9-methyl-3-oxa-9-azatricyclo[3.2.1.02,4]non-7-yl α-hydroxy-α-(hydroxymethyl)benzeneacetate | image = Anisodine.png | tradename = | pregnancy_category = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 52646-92-1 | ATC_prefix = none | ATC_suffix = | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C17H21NO5/c1-18-12-7-11(8-13(18)15-14(12)23-15)22-16(20)17(21,9-19)10-5-3-2-4-6-10/h2-6,11-15,19,21H,7-9H2,1H3/t11?,12-,13+,14-,15+,17-/m1/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = JEJREKXHLFEVHN-QDXGGTILSA-N | PubChem = 4105431 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 9791461 | C=17 | H=21 | N=1 | O=5 | molecular_weight = 319.35 g/mol | smiles = O=C(OC1CC2N(C(C1)C3OC23)C)C(O)(c4ccccc4)CO }}Anisodine, also known as daturamine and α-hydroxyscopolamine, is an antispasmodic and anticholinergic drug used in the treatment of acute circulatory shock in China.[1][2] It is a tropane alkaloid and is found naturally in species of the Solanaceae family of plants.[2] Anisodine acts as a muscarinic acetylcholine receptor antagonist and α1-adrenergic receptor agonist.[1] See also
References1. ^1 {{cite journal |vauthors=Varma DR, Yue TL | title = Adrenoceptor blocking properties of atropine-like agents anisodamine and anisodine on brain and cardiovascular tissues of rats | journal = British Journal of Pharmacology | volume = 87 | issue = 3 | pages = 587–94 |date=March 1986 | pmid = 2879586 | pmc = 1916562 | doi = 10.1111/j.1476-5381.1986.tb10201.x| url = }} {{Adrenergic receptor modulators}}{{Muscarinic acetylcholine receptor modulators}}{{cardiovascular-drug-stub}}2. ^1 {{cite book | url = https://books.google.com/books?id=DeX7jgInYFMC&lpg=RA1-PA152&dq=anisodine&lr=&as_brr=3&pg=RA1-PA152#v=onepage&q=anisodine&f=false | title = Dictionary of pharmacological agents - Google Books | format = | work = | accessdate = }} 5 : Alpha-adrenergic agonists|Epoxides|Muscarinic antagonists|Tropane alkaloids|Tropane alkaloids found in Solanaceae |
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