| 词条 | Anonychia |
| 释义 |
| name = Anonychia | synonyms = | image = | caption = | pronounce = | field = Dermatology | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }} Anonychia is the absence of nails, an anomaly, which may be the result of a congenital ectodermal defect, ichthyosis, severe infection, severe allergic contact dermatitis, self-inflicted trauma, Raynaud phenomenon, lichen planus, epidermolysis bullosa, or severe exfoliative diseases.[1]{{rp|784}} Congenital formThis is rare and is usually due to mutations in the R-spondin 4 (RSPO4) gene which is located on the short arm of chromosome 20 (20p13).[2] Clinically it is manifest by the absence (anonychia) or hypoplasia (hyponychia) of finger- and/or toenails. See also
References1. ^James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. {{ISBN|0-7216-2921-0}}. 2. ^Khan TN, Klar J, Nawaz S, Jameel M, Tariq M, Malik NA, Baig SM, Dahl N (2012) Novel missense mutation in the RSPO4 gene in congenital hyponychia and evidence for a polymorphic initiation codon (p.M1I). BMC Med Genet 13(1):120 External links{{Medical resources| DiseasesDB = | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = | ICD10 = {{ICD10|L|60|8|l|60}}, {{ICD10|Q|84|3|q|80}} | ICD9 = {{ICD9|703.8}}, {{ICD9|757.5}} }}{{Disorders of skin appendages}}{{Congenital malformations and deformations of skin appendages}}{{skin-appendage-stub}} 1 : Conditions of the skin appendages |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。