释义 |
- Interactions
- References
- Further reading
- External links
{{Infobox_gene}}AP-2 complex subunit alpha-2 is a protein that in humans is encoded by the AP2A2 gene.[1][2][3] Interactions AP2A2 has been shown to interact with EPN1[4] and SHC1.[5] References 1. ^{{cite journal | vauthors = Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME | title = Huntingtin interacts with a family of WW domain proteins | journal = Human Molecular Genetics | volume = 7 | issue = 9 | pages = 1463–74 | date = Sep 1998 | pmid = 9700202 | pmc = | doi = 10.1093/hmg/7.9.1463 }} 2. ^{{cite journal | vauthors = Robinson MS | title = Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins) | journal = The Journal of Cell Biology | volume = 108 | issue = 3 | pages = 833–42 | date = Mar 1989 | pmid = 2564002 | pmc = 2115374 | doi = 10.1083/jcb.108.3.833 }} 3. ^{{cite web | title = Entrez Gene: AP2A2 adaptor-related protein complex 2, alpha 2 subunit| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=161| accessdate = }} 4. ^{{cite journal | vauthors = Chen H, Fre S, Slepnev VI, Capua MR, Takei K, Butler MH, Di Fiore PP, De Camilli P | title = Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis | journal = Nature | volume = 394 | issue = 6695 | pages = 793–7 | date = Aug 1998 | pmid = 9723620 | doi = 10.1038/29555 }} 5. ^{{cite journal | vauthors = Okabayashi Y, Sugimoto Y, Totty NF, Hsuan J, Kido Y, Sakaguchi K, Gout I, Waterfield MD, Kasuga M | title = Interaction of Shc with adaptor protein adaptins | journal = The Journal of Biological Chemistry | volume = 271 | issue = 9 | pages = 5265–9 | date = Mar 1996 | pmid = 8617812 | doi = 10.1074/jbc.271.9.5265 }}
Further reading {{refbegin | 2}}- {{cite journal | vauthors = Kirchhausen T | title = Clathrin | journal = Annual Review of Biochemistry | volume = 69 | issue = | pages = 699–727 | year = 2000 | pmid = 10966473 | doi = 10.1146/annurev.biochem.69.1.699 }}
- {{cite journal | vauthors = Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T | title = Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones | journal = DNA Research | volume = 9 | issue = 3 | pages = 99–106 | date = Jun 2002 | pmid = 12168954 | doi = 10.1093/dnares/9.3.99 }}
- {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | date = Jan 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
- {{cite journal | vauthors = David C, McPherson PS, Mundigl O, de Camilli P | title = A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 93 | issue = 1 | pages = 331–5 | date = Jan 1996 | pmid = 8552632 | pmc = 40232 | doi = 10.1073/pnas.93.1.331 }}
- {{cite journal | vauthors = Okabayashi Y, Sugimoto Y, Totty NF, Hsuan J, Kido Y, Sakaguchi K, Gout I, Waterfield MD, Kasuga M | title = Interaction of Shc with adaptor protein adaptins | journal = The Journal of Biological Chemistry | volume = 271 | issue = 9 | pages = 5265–9 | date = Mar 1996 | pmid = 8617812 | doi = 10.1074/jbc.271.9.5265 }}
- {{cite journal | vauthors = Benmerah A, Bégue B, Dautry-Varsat A, Cerf-Bensussan N | title = The ear of alpha-adaptin interacts with the COOH-terminal domain of the Eps 15 protein | journal = The Journal of Biological Chemistry | volume = 271 | issue = 20 | pages = 12111–6 | date = May 1996 | pmid = 8662627 | doi = 10.1074/jbc.271.20.12111 }}
- {{cite journal | vauthors = van Delft S, Schumacher C, Hage W, Verkleij AJ, van Bergen en Henegouwen PM | title = Association and colocalization of Eps15 with adaptor protein-2 and clathrin | journal = The Journal of Cell Biology | volume = 136 | issue = 4 | pages = 811–21 | date = Feb 1997 | pmid = 9049247 | pmc = 2132490 | doi = 10.1083/jcb.136.4.811 }}
- {{cite journal | vauthors = Ramjaun AR, Micheva KD, Bouchelet I, McPherson PS | title = Identification and characterization of a nerve terminal-enriched amphiphysin isoform | journal = The Journal of Biological Chemistry | volume = 272 | issue = 26 | pages = 16700–6 | date = Jun 1997 | pmid = 9195986 | doi = 10.1074/jbc.272.26.16700 }}
- {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | date = Oct 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
- {{cite journal | vauthors = Chen H, Fre S, Slepnev VI, Capua MR, Takei K, Butler MH, Di Fiore PP, De Camilli P | title = Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis | journal = Nature | volume = 394 | issue = 6695 | pages = 793–7 | date = Aug 1998 | pmid = 9723620 | doi = 10.1038/29555 }}
- {{cite journal | vauthors = Berlioz-Torrent C, Shacklett BL, Erdtmann L, Delamarre L, Bouchaert I, Sonigo P, Dokhelar MC, Benarous R | title = Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins | journal = Journal of Virology | volume = 73 | issue = 2 | pages = 1350–61 | date = Feb 1999 | pmid = 9882340 | pmc = 103959 | doi = }}
- {{cite journal | vauthors = Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Research | volume = 5 | issue = 6 | pages = 355–64 | date = Dec 1998 | pmid = 10048485 | doi = 10.1093/dnares/5.6.355 }}
- {{cite journal | vauthors = Traub LM, Downs MA, Westrich JL, Fremont DH | title = Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 96 | issue = 16 | pages = 8907–12 | date = Aug 1999 | pmid = 10430869 | pmc = 17706 | doi = 10.1073/pnas.96.16.8907 }}
- {{cite journal | vauthors = Page LJ, Sowerby PJ, Lui WW, Robinson MS | title = Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin | journal = The Journal of Cell Biology | volume = 146 | issue = 5 | pages = 993–1004 | date = Sep 1999 | pmid = 10477754 | pmc = 2169493 | doi = 10.1083/jcb.146.5.993 }}
- {{cite journal | vauthors = Kim ST, Lim DS, Canman CE, Kastan MB | title = Substrate specificities and identification of putative substrates of ATM kinase family members | journal = The Journal of Biological Chemistry | volume = 274 | issue = 53 | pages = 37538–43 | date = Dec 1999 | pmid = 10608806 | doi = 10.1074/jbc.274.53.37538 }}
- {{cite journal | vauthors = Slepnev VI, Ochoa GC, Butler MH, De Camilli P | title = Tandem arrangement of the clathrin and AP-2 binding domains in amphiphysin 1 and disruption of clathrin coat function by amphiphysin fragments comprising these sites | journal = The Journal of Biological Chemistry | volume = 275 | issue = 23 | pages = 17583–9 | date = Jun 2000 | pmid = 10748223 | doi = 10.1074/jbc.M910430199 }}
- {{cite journal | vauthors = Jullien-Flores V, Mahé Y, Mirey G, Leprince C, Meunier-Bisceuil B, Sorkin A, Camonis JH | title = RLIP76, an effector of the GTPase Ral, interacts with the AP2 complex: involvement of the Ral pathway in receptor endocytosis | journal = Journal of Cell Science | volume = 113 | issue = 16 | pages = 2837–44 | date = Aug 2000 | pmid = 10910768 | doi = }}
{{refend}}External links{{PDB Gallery|geneid=161}}{{gene-11-stub}} |