“AQP7”的意思、由来-开放百科全书

Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in thermoregulation in the form of perspiration and sperm function.^[2]

References

1. ^{{cite journal |vauthors=Ishibashi K, Kuwahara M, Gu Y, Kageyama Y, Tohsaka A, Suzuki F, Marumo F, Sasaki S | title = Cloning and functional expression of a new water channel abundantly expressed in the testis permeable to water, glycerol, and urea | journal = J Biol Chem | volume = 272 | issue = 33 | pages = 20782–6 |date=Sep 1997 | pmid = 9252401 | pmc = | doi =10.1074/jbc.272.33.20782 }}
2. ^¹{{cite web | title = Entrez Gene: AQP7 aquaporin 7| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=364| accessdate = }}

Further reading

{{cite journal |vauthors=Dibas AI, Mia AJ, Yorio T |title=Aquaporins (water channels): role in vasopressin-activated water transport |journal=Proc. Soc. Exp. Biol. Med. |volume=219 |issue= 3 |pages= 183–99 |year= 1998 |pmid= 9824541 |doi= 10.3181/00379727-219-44332}}

{{cite journal | author=Kuriyama H |title=Molecular cloning and expression of a novel human aquaporin from adipose tissue with glycerol permeability |journal=Biochem. Biophys. Res. Commun. |volume=241 |issue= 1 |pages= 53–8 |year= 1998 |pmid= 9405233 |doi= 10.1006/bbrc.1997.7769 |name-list-format=vanc| author2=Kawamoto S | author3=Ishida N | display-authors=3 | last4=Ohno | first4=Ikko | last5=Mita | first5=Shiro | last6=Matsuzawa | first6=Yuji | last7=Matsubara | first7=Kenichi | last8=Okubo | first8=Kousaku }}

{{cite journal | author=Ishibashi K |title=Molecular characterization of human Aquaporin-7 gene and its chromosomal mapping |journal=Biochim. Biophys. Acta |volume=1399 |issue= 1 |pages= 62–6 |year= 1998 |pmid= 9714739 |doi= 10.1016/s0167-4781(98)00094-3|name-list-format=vanc| author2=Yamauchi K | author3=Kageyama Y | display-authors=3 | last4=Saito-Ohara | first4=F | last5=Ikeuchi | first5=T | last6=Marumo | first6=F | last7=Sasaki | first7=S }}

{{cite journal |vauthors=Suzuki-Toyota F, Ishibashi K, Yuasa S |title=Immunohistochemical localization of a water channel, aquaporin 7 (AQP7), in the rat testis |journal=Cell Tissue Res. |volume=295 |issue= 2 |pages= 279–85 |year= 1999 |pmid= 9931374 |doi=10.1007/s004410051234 }}

{{cite journal | author=Kondo H |title=Human aquaporin adipose (AQPap) gene. Genomic structure, promoter analysis and functional mutation |journal=Eur. J. Biochem. |volume=269 |issue= 7 |pages= 1814–26 |year= 2002 |pmid= 11952783 |doi=10.1046/j.1432-1033.2002.02821.x |name-list-format=vanc| author2=Shimomura I | author3=Kishida K | display-authors=3 | last4=Kuriyama | first4=Hiroshi | last5=Makino | first5=Yasunaka | last6=Nishizawa | first6=Hitoshi | last7=Matsuda | first7=Morihiro | last8=Maeda | first8=Norikazu | last9=Nagaretani | first9=Hiroyuki }}

{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}

{{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki }}

{{cite journal | author=Humphray SJ |title=DNA sequence and analysis of human chromosome 9 |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465 | pmc=2734081 |name-list-format=vanc| author2=Oliver K | author3=Hunt AR | display-authors=3 | last4=Plumb | first4=R. W. | last5=Loveland | first5=J. E. | last6=Howe | first6=K. L. | last7=Andrews | first7=T. D. | last8=Searle | first8=S. | last9=Hunt | first9=S. E. }}

{{cite journal | author=Fortna A |title=Lineage-Specific Gene Duplication and Loss in Human and Great Ape Evolution |journal=PLoS Biol. |volume=2 |issue= 7 |pages= E207 |year= 2006 |pmid= 15252450 |doi= 10.1371/journal.pbio.0020207 | pmc=449870 |name-list-format=vanc| author2=Kim Y | author3=MacLaren E | display-authors=3 | last4=Marshall | first4=Kriste | last5=Hahn | first5=Gretchen | last6=Meltesen | first6=Lynne | last7=Brenton | first7=Matthew | last8=Hink | first8=Raquel | last9=Burgers | first9=Sonya }}

{{cite journal |vauthors=Marrades MP, Milagro FI, Martínez JA, Moreno-Aliaga MJ |title=Differential expression of aquaporin 7 in adipose tissue of lean and obese high fat consumers |journal=Biochem. Biophys. Res. Commun. |volume=339 |issue= 3 |pages= 785–9 |year= 2006 |pmid= 16325777 |doi= 10.1016/j.bbrc.2005.11.080 }}

{{cite journal | author=Prudente S |title=A functional variant of the adipocyte glycerol channel aquaporin 7 gene is associated with obesity and related metabolic abnormalities |journal=Diabetes |volume=56 |issue= 5 |pages= 1468–74 |year= 2007 |pmid= 17351148 |doi= 10.2337/db06-1389 |name-list-format=vanc| author2=Flex E | author3=Morini E | display-authors=3 | last4=Turchi | first4=F. | last5=Capponi | first5=D. | last6=De Cosmo | first6=S. | last7=Tassi | first7=V. | last8=Guida | first8=V. | last9=Avogaro | first9=A. }}

{{cite journal | author=Ceperuelo-Mallafré V |title=Adipose tissue expression of the glycerol channel aquaporin-7 gene is altered in severe obesity but not in type 2 diabetes |journal=J. Clin. Endocrinol. Metab. |volume=92 |issue= 9 |pages= 3640–5 |year= 2007 |pmid= 17566090 |doi= 10.1210/jc.2007-0531 |name-list-format=vanc| author2=Miranda M | author3=Chacón MR | display-authors=3 | last4=Vilarrasa | first4=N. | last5=Megia | first5=A. | last6=Gutierrez | first6=C. | last7=Fernandez-Real | first7=J. M. | last8=Gomez | first8=J. M. | last9=Caubet | first9=E. }}

See also

References

Further reading

External links