| 词条 | Aquayamycin |
| 释义 |
| verifiedrevid = 458036550 | ImageFile=Aquayamycin.svg | ImageSize=150px | IUPACName=(3R,4aR,12bS)-9-[(2R,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]-3,4a,8,12b-tetrahydroxy-3-methyl-2,4-dihydrobenzo[a]anthracene-1,7,12-trione | OtherNames= | Reference=[1] |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo=26055-63-0 | PubChem=73441 | SMILES=C[C@@H]1[C@H]([C@@H](C[C@@H](O1)C2=C(C3=C(C=C2)C(=O)C4=C(C3=O)C=C[C@]5([C@@]4(C(=O)C[C@](C5)(C)O)O)O)O)O)O | MeSHName=aquayamycin | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 66147 | InChI = 1/C25H26O10/c1-10-19(28)14(26)7-15(35-10)11-3-4-12-17(20(11)29)21(30)13-5-6-24(33)9-23(2,32)8-16(27)25(24,34)18(13)22(12)31/h3-6,10,14-15,19,26,28-29,32-34H,7-9H2,1-2H3/t10-,14-,15-,19-,23+,24+,25+/m1/s1 | InChIKey = KCOULPRVOZDQEL-IFNZWHIZBY | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C25H26O10/c1-10-19(28)14(26)7-15(35-10)11-3-4-12-17(20(11)29)21(30)13-5-6-24(33)9-23(2,32)8-16(27)25(24,34)18(13)22(12)31/h3-6,10,14-15,19,26,28-29,32-34H,7-9H2,1-2H3/t10-,14-,15-,19-,23+,24+,25+/m1/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = KCOULPRVOZDQEL-IFNZWHIZSA-N |Section2={{Chembox Properties | Formula= C25H26O10 | MolarMass= 486.47 g/mol | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }}Aquayamycin is an anthraquinone derivative.[2] It is an inhibitor of the enzyme tyrosine hydroxylase. Saquayamycins (saquayamycins A, B, C and D) are antibiotics of the aquayamycin group found in Streptomyces nodosus cultures broth.[3]References1. ^[https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=73441 Aquayamycin - Compound Summary], PubChem. {{Monoamine metabolism modulators}}{{nervous-system-drug-stub}}2. ^{{Cite journal | last1 = Sezaki | first1 = M. | last2 = Kondo | first2 = S. | last3 = Maeda | first3 = K. | last4 = Umezawa | first4 = H. | last5 = Ono | first5 = M. | title = The structure of aquayamycin | doi = 10.1016/S0040-4020(01)98726-5 | journal = Tetrahedron | volume = 26 | issue = 22 | pages = 5171–5190 | year = 1970 | pmid = 5499897| pmc = }} 3. ^{{Cite journal | doi = 10.7164/antibiotics.38.1171 | last1 = Uchida | first1 = T. | last2 = Imoto | first2 = M. | last3 = Watanabe | first3 = Y. | last4 = Miura | first4 = K. | last5 = Dobashi | first5 = T. | last6 = Matsuda | first6 = N. | last7 = Sawa | first7 = T. | last8 = Naganawa | first8 = H. | last9 = Hamada | first9 = M. | last10 = Takeuchi | first10 = T. | last11 = Umezawa | first11 = H. | title = Saquayamycins, new aquayamycin-group antibiotics | journal = The Journal of Antibiotics | volume = 38 | issue = 9 | pages = 1171–1181 | year = 1985 | pmid = 3840796}} 4 : Anthraquinone glycosides|Tyrosine hydroxylase inhibitors|Triketones|Angucyclines |
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