“ARFGEF2”的意思、由来-开放百科全书

ARFGEF2 has been shown to interact with ARFGEF1,^[3] PRKAR1A^[4] and PRKAR2A.^[4]

References

1. ^{{cite journal | vauthors = Togawa A, Morinaga N, Ogasawara M, Moss J, Vaughan M | title = Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors | journal = The Journal of Biological Chemistry | volume = 274 | issue = 18 | pages = 12308–15 | date = Apr 1999 | pmid = 10212200 | pmc = | doi = 10.1074/jbc.274.18.12308 }}
2. ^¹{{cite web | title = Entrez Gene: ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10564| accessdate = }}
3. ^{{cite journal | vauthors = Yamaji R, Adamik R, Takeda K, Togawa A, Pacheco-Rodriguez G, Ferrans VJ, Moss J, Vaughan M | title = Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 6 | pages = 2567–72 | date = Mar 2000 | pmid = 10716990 | pmc = 15969 | doi = 10.1073/pnas.97.6.2567 }}
4. ^¹{{cite journal | vauthors = Li H, Adamik R, Pacheco-Rodriguez G, Moss J, Vaughan M | title = Protein kinase A-anchoring (AKAP) domains in brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2) | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 100 | issue = 4 | pages = 1627–32 | date = Feb 2003 | pmid = 12571360 | pmc = 149883 | doi = 10.1073/pnas.0337678100 }}

Further reading

{{cite journal | vauthors = Yamaji R, Adamik R, Takeda K, Togawa A, Pacheco-Rodriguez G, Ferrans VJ, Moss J, Vaughan M | title = Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 6 | pages = 2567–72 | date = Mar 2000 | pmid = 10716990 | pmc = 15969 | doi = 10.1073/pnas.97.6.2567 }}

{{cite journal | vauthors = Kamei Y, Takeda Y, Teramoto K, Tsutsumi O, Taketani Y, Watanabe K | title = Human NB-2 of the contactin subgroup molecules: chromosomal localization of the gene (CNTN5) and distinct expression pattern from other subgroup members | journal = Genomics | volume = 69 | issue = 1 | pages = 113–9 | date = Oct 2000 | pmid = 11013081 | doi = 10.1006/geno.2000.6310 }}

{{cite journal | vauthors = Pacheco-Rodriguez G, Moss J, Vaughan M | title = BIG1 and BIG2: brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors | journal = Methods in Enzymology | volume = 345 | issue = | pages = 397–404 | year = 2002 | pmid = 11665623 | doi = 10.1016/S0076-6879(02)45032-X }}

{{cite journal | vauthors = Shinotsuka C, Yoshida Y, Kawamoto K, Takatsu H, Nakayama K | title = Overexpression of an ADP-ribosylation factor-guanine nucleotide exchange factor, BIG2, uncouples brefeldin A-induced adaptor protein-1 coat dissociation and membrane tubulation | journal = The Journal of Biological Chemistry | volume = 277 | issue = 11 | pages = 9468–73 | date = Mar 2002 | pmid = 11777925 | doi = 10.1074/jbc.M112427200 }}

{{cite journal | vauthors = Shinotsuka C, Waguri S, Wakasugi M, Uchiyama Y, Nakayama K | title = Dominant-negative mutant of BIG2, an ARF-guanine nucleotide exchange factor, specifically affects membrane trafficking from the trans-Golgi network through inhibiting membrane association of AP-1 and GGA coat proteins | journal = Biochemical and Biophysical Research Communications | volume = 294 | issue = 2 | pages = 254–60 | date = Jun 2002 | pmid = 12051703 | doi = 10.1016/S0006-291X(02)00456-4 }}

{{cite journal | vauthors = Li H, Adamik R, Pacheco-Rodriguez G, Moss J, Vaughan M | title = Protein kinase A-anchoring (AKAP) domains in brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2) | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 100 | issue = 4 | pages = 1627–32 | date = Feb 2003 | pmid = 12571360 | pmc = 149883 | doi = 10.1073/pnas.0337678100 }}

{{cite journal | vauthors = Sheen VL, Ganesh VS, Topcu M, Sebire G, Bodell A, Hill RS, Grant PE, Shugart YY, Imitola J, Khoury SJ, Guerrini R, Walsh CA | title = Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex | journal = Nature Genetics | volume = 36 | issue = 1 | pages = 69–76 | date = Jan 2004 | pmid = 14647276 | doi = 10.1038/ng1276 }}

{{cite journal | vauthors = Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM | title = Functional proteomics mapping of a human signaling pathway | journal = Genome Research | volume = 14 | issue = 7 | pages = 1324–32 | date = Jul 2004 | pmid = 15231748 | pmc = 442148 | doi = 10.1101/gr.2334104 }}

{{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 33 | pages = 12130–5 | date = Aug 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 }}

{{cite journal | vauthors = Xu KF, Shen X, Li H, Pacheco-Rodriguez G, Moss J, Vaughan M | title = Interaction of BIG2, a brefeldin A-inhibited guanine nucleotide-exchange protein, with exocyst protein Exo70 | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 102 | issue = 8 | pages = 2784–9 | date = Feb 2005 | pmid = 15705715 | pmc = 549493 | doi = 10.1073/pnas.0409871102 }}

{{cite journal | vauthors = Lu J, Tiao G, Folkerth R, Hecht J, Walsh C, Sheen V | title = Overlapping expression of ARFGEF2 and Filamin A in the neuroependymal lining of the lateral ventricles: insights into the cause of periventricular heterotopia | journal = The Journal of Comparative Neurology | volume = 494 | issue = 3 | pages = 476–84 | date = Jan 2006 | pmid = 16320251 | doi = 10.1002/cne.20806 }}

{{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | date = Nov 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }}

{{cite journal | vauthors = Islam A, Shen X, Hiroi T, Moss J, Vaughan M, Levine SJ | title = The brefeldin A-inhibited guanine nucleotide-exchange protein, BIG2, regulates the constitutive release of TNFR1 exosome-like vesicles | journal = The Journal of Biological Chemistry | volume = 282 | issue = 13 | pages = 9591–9 | date = Mar 2007 | pmid = 17276987 | doi = 10.1074/jbc.M607122200 }}

{{cite journal | vauthors = Kuroda F, Moss J, Vaughan M | title = Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 104 | issue = 9 | pages = 3201–6 | date = Feb 2007 | pmid = 17360629 | pmc = 1805514 | doi = 10.1073/pnas.0611696104 }}

Function

Interactions

References

External links

Further reading