| 释义 |
- Function
- Interactions
- References
- External links
- Further reading
{{Infobox_gene}}Rho guanine nucleotide exchange factor (GEF) 3, also known as ARHGEF3, is a human gene.[1] Function Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to the NET1A protein.[1] Interactions ARHGEF3 has been shown to interact with RHOA[2] and RHOB.[2] References 1. ^1 {{cite web | title = Entrez Gene: ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50650| accessdate = }}
2. ^1 {{cite journal | vauthors = Arthur WT, Ellerbroek SM, Der CJ, Burridge K, Wennerberg K | title = XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC | journal = J. Biol. Chem. | volume = 277 | issue = 45 | pages = 42964–72 | date = Nov 2002 | pmid = 12221096 | doi = 10.1074/jbc.M207401200 }}
External links- {{UCSC gene info|ARHGEF3}}
Further reading {{refbegin | 2}}- {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | year = 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
- {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | year = 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
- {{cite journal | vauthors = Thiesen S, Kübart S, Ropers HH, Nothwang HG | title = Isolation of two novel human RhoGEFs, ARHGEF3 and ARHGEF4, in 3p13-21 and 2q22 | journal = Biochem. Biophys. Res. Commun. | volume = 273 | issue = 1 | pages = 364–9 | year = 2000 | pmid = 10873612 | doi = 10.1006/bbrc.2000.2925 }}
- {{cite journal | vauthors = Hartley JL, Temple GF, Brasch MA | title = DNA Cloning Using In Vitro Site-Specific Recombination | journal = Genome Res. | volume = 10 | issue = 11 | pages = 1788–95 | year = 2001 | pmid = 11076863 | pmc = 310948 | doi = 10.1101/gr.143000 }}
- {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs | journal = Genome Res. | volume = 11 | issue = 3 | pages = 422–35 | year = 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}
- {{cite journal | vauthors = Arthur WT, Ellerbroek SM, Der CJ, Burridge K, Wennerberg K | title = XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC | journal = J. Biol. Chem. | volume = 277 | issue = 45 | pages = 42964–72 | year = 2003 | pmid = 12221096 | doi = 10.1074/jbc.M207401200 }}
- {{cite journal | vauthors = Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A | title = From ORFeome to Biology: A Functional Genomics Pipeline | journal = Genome Res. | volume = 14 | issue = 10B | pages = 2136–44 | year = 2004 | pmid = 15489336 | pmc = 528930 | doi = 10.1101/gr.2576704 }}
- {{cite journal | vauthors = Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S | title = The LIFEdb database in 2006 | journal = Nucleic Acids Res. | volume = 34 | issue = Database issue | pages = D415–8 | year = 2006 | pmid = 16381901 | pmc = 1347501 | doi = 10.1093/nar/gkj139 }}
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