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词条 Arylacetonitrilase
释义

  1. References

{{enzyme
| Name = arylacetonitrilase
| EC_number = 3.5.5.5
| CAS_number = 132053-06-6
| IUBMB_EC_number = 3/5/5/5
| GO_code = 0047428
| image =
| width =
| caption =
}}

In enzymology, an arylacetonitrilase ({{EC number|3.5.5.5}}) is an enzyme that catalyzes the chemical reaction

4-chlorophenylacetonitrile + 2 H2O 4-chlorophenylacetate + NH3

Thus, the two substrates of this enzyme are 4-chlorophenylacetonitrile and H2O, whereas its two products are 4-chlorophenylacetate and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in nitriles. The systematic name of this enzyme class is arylacetonitrile aminohydrolase. This enzyme participates in cyanoamino acid metabolism.

References

  • {{cite journal | vauthors = Mauger J, Nagasawa T, Yamada H | last-author-amp = yes | date = 1990 | title = Occurrence of a novel nitrilase, arylacetonitrilase, in Alcaligenes faecalis JM3 | journal = Arch. Microbiol. | volume = 155 | pages = 1–6 | doi = 10.1007/BF00291265 }}
  • {{cite journal | vauthors = Nagasawa T, Mauger J, Yamada H | date = 1990 | title = A novel nitrilase, arylacetonitrilase, of Alcaligenes faecalis JM3 Purification and characterization | journal = Eur. J. Biochem. | volume = 194 | pages = 765–72 | pmid = 2269298 | doi = 10.1111/j.1432-1033.1990.tb19467.x | issue = 3 }}
{{Carbon-nitrogen non-peptide hydrolases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{3.5-enzyme-stub}}

2 : EC 3.5.5|Enzymes of unknown structure

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