| 释义 |
Arylalkanolamines (ArROHNR2) are a class of medicinal molecules that are structurally related to one another in certain respects. Detailed understanding of their structure-activity relationship is expected to aid in drug discovery. {{Citation needed|date=December 2009}} Phen(Aryl)alkanolamine. All molecules are α-aromatic-alcohols unless stated otherwise. Compound | Group | 1/2/3° OH | Α/Β/Γ/Δ | Α/Β/Γ/Δ | N | Type of Pharmacology | | PRC025 | 3-OH-2-BN-A | 2° | γ-aminoalcohol | β | NHMe2 | SN(D)RI | | PRC200-SS | PP-3-A | 2° | " | α,β | NHMe | NS(D)RI | | Pridinol | " | 3° | " | NC5H10 | Anticholinergic (NMDA?) | | Trihexyphenidyl (aka Benzhexol) | " | " | " | " | " | | Biperiden | " | " | " | " | " | | BDPC | cyclohexanol | 3° | δ-aminoalcohol | γ,δ | NMe2 | μ/delta-opioid agonist | | Tramadol | " | " | 3 | α-arylalcohol | " | μ-opioid agonist(prodrug, M1SNRI | | Venlafaxine | " | " | 2 | β-arylalcohol | " | SNRI | | Ciramadol | " | 2° | 3 | γ-arylalcohol | " | μ-opioid mixed ant/agonist | | Phenylpropanolamine | PP-2-A | 2° | 2 | NH2 | nor/adrenergic releaser | | Cathine | " | " | " | " | nor/adrenergic releaser | | Ephedrine | " | " | β-aminoalcohol | NHMe | nor/adrenergic releaser | | Pseudoephedrine | " | " | " | " | nor/adrenergic releaser | | Dopamine | " | " | " | " | endogenous neurotransmitter | | Epinephrine | ArE-2-A | " | " | " | neurotransmitter, also a hormone | | Norepinephrine | " | " | " | NH2 | neurotransmitter | | Synephrine | " | " | " | " | α1 agonist | | Phenylephrine | " | " | " | " | α1 agonist | | Levalbuterol | " | " | " | NH(t-Bu) | β-agonist | | Clenbuterol | " | " | " | " | " | | Haloperidol | Piperidinol | 3° | δ | 4,4 | piper | DA antagonist | | Loperamide(Imodium AD) | " | " | " | " | " | μ-opioid agonist. |
1 : Beta-adrenergic agonists |