| 词条 | Benzylpenicilloyl polylysine |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 459813303 | IUPAC_name = [2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate : L-Lysine homopolymer | image = Benzylpenicilloyl polylysine (structural diagram).png | width = | alt = | image2 = | width2 = | drug_name = | tradename = Pre-Pen | licence_EU = | licence_US = Pre-Pen | DailyMedID = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = Rx-only | legal_status = | dependency_liability = | routes_of_administration = Liquid intradermal | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 31855-75-1 | CAS_supplemental = | ATCvet = | ATC_prefix = none | ATC_suffix = | ATC_supplemental = | PubChem = | PubChemSubstance = | IUPHAR_ligand = | DrugBank_Ref = {{drugbankcite|changed|drugbank}} | DrugBank = DB00895 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = none | UNII_Ref = {{fdacite|correct|FDA}} | KEGG_Ref = {{keggcite|correct|kegg}} | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 1201779 | synonyms = Pre-Pen | chemical_formula = | molecular_weight = | SMILES = | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = | density = | melting_point = | melting_high = | melting_notes = | boiling_point = | boiling_notes = | solubility = | specific_rotation = | sec_combustion = }}Benzylpenicilloyl polylysine (Pre-Pen) is used as a skin test before the administration of penicillin. It is used to detect the immunoglobulin E antibodies.[1][2] The chemical structure consists of the benzylpenicilloyl group attached to a polymer of L-lysine.[3][4][5] References1. ^http://www.pharmgkb.org/do/serve?objId=PA164754810&objCls=Drug 2. ^http://www.drugbank.ca/drugs/DB00895 3. ^{{cite journal |author1=Vemuri, Preeti |author2=Harris, Kathleen E. |author3=Suh, Lydia A. |author4=Grammer, Leslie C. | title = Preparation of benzylpenicilloyl-polylysine: a preliminary study | journal = Allergy and Asthma Proceedings | year = 2004 | volume = 25 | issue = 3 | pages = 165–168}} 4. ^{{Cite journal| pmid = 6874593| volume = 36| issue = 6| pages = 709–14| last = Goldschmidt| first = BM| author2=BB Levine| title = The preparation and determination of structure of benzylpenicilloyl compounds used in skin-testing for penicillin allergy.| journal = Journal of Antibiotics| year=1983| doi=10.7164/antibiotics.36.709}} 5. ^http://ainotes.wikispaces.com/file/view/PREPEN_Package_Insert.pdf 1 : Beta-lactam antibiotics |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。